大杨桃螺（学名：Harpa major），是新腹足目杨桃螺科杨桃螺属的一种。主要分布于马来西亚、印度尼西亚、**，常栖息在浅海、沿岸。

Harpa major, common name large harp, or major harp, is a species of large predatory sea snail, a marine gastropod mollusks in the family Harpidae, the harp snails and their allies.