Angiomyolipoma

Myoid cells with clear cytoplasm spinning off of large vessels in a background of mature fat: the classic microscopic features of angiomyolipoma.

Angiomyolipomas are the most common benign tumour of the kidney and are composed of blood vessels, smooth muscle cells and fat cells. Angiomyolipomas are strongly associated with the genetic disease tuberous sclerosis, in which most individuals will have several angiomyolipomas affecting both kidneys. They are also commonly found in women with the rare lung disease lymphangioleiomyomatosis. Angiomyolipomas are less commonly found in the liver and rarely in other organs. Whether associated with these diseases or sporadic, angiomyolipomas are caused by mutations in either the TSC1 or TSC2 genes, which govern cell growth and proliferation.

单词	Angiomyolipoma
释义	Angiomyolipoma 原声例句 Osmosis-神经 A large angiomyolipoma can cause flank pain, a lymphangioleiomyomatosis in the lungs, can cause shortness of breath, and a retinal hamartoma can cause vision changes. 巨大的血管平滑肌脂肪瘤可引起腹痛；肺淋巴管平滑肌瘤可引起呼吸短促；视网膜错构瘤会导致视力改变。英语百科 Angiomyolipoma Angiomyolipomas are the most common benign tumour of the kidney and are composed of blood vessels, smooth muscle cells and fat cells. Angiomyolipomas are strongly associated with the genetic disease tuberous sclerosis, in which most individuals will have several angiomyolipomas affecting both kidneys. They are also commonly found in women with the rare lung disease lymphangioleiomyomatosis. Angiomyolipomas are less commonly found in the liver and rarely in other organs. Whether associated with these diseases or sporadic, angiomyolipomas are caused by mutations in either the TSC1 or TSC2 genes, which govern cell growth and proliferation.
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