H2受体阻抗剂 H2 antagonist
（重定向自H2 receptor antagonist）
![西咪替丁，H2受体阻抗剂的原型药](/Images/godic/202501/16/Cimetidine-xtal-3D-balls5032.png")
H2受体阻抗剂（英语：H2 antagonist）是一系列用于阻断组织胺作用于胃的壁细胞（parietal cells）、减少壁细胞分泌胃酸的药物。H2受体阻抗剂用于治疗消化不良，但现在已经有效果更好的氢离子帮浦阻断剂。
在美国，美国食品药物管理局核准低剂量的西咪替丁、雷尼替丁、法莫替丁和尼扎替丁（Nizatidine）不用处方就可以取得。
H2 receptor antagonist
中文百科
英语百科
H2 antagonist H2受体阻抗剂
（重定向自H2 receptor antagonist）
![Cimetidina, el prototipo de los antagonistas de los receptores para la H2.](/Images/godic/202501/16/Cimetidine_structure.svg5032.png")
H2 antagonists, also called H2 blockers, are a class of medications that block the action of histamine at the histamine H2 receptors of the parietal cells in the stomach. This decreases the production of stomach acid. H2 antagonists can be used in the treatment of dyspepsia, but have been surpassed by the more effective proton pump inhibitors. They are also used to treat peptic ulcer disease and gastroesophageal reflux disease.
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