嵌齿象科（Gomphotheriidae）是长鼻目中已经灭绝的一个科，曾经广泛的分布在北美洲，也有一些种类分布在欧亚大陆，生存于中新世至上新世。

嵌齿象类与象科的牙齿构造的相当不同，特别是上颚臼齿的咀嚼面。大部分的嵌齿象类拥有4支象牙，而且拥有后缩的脸与鼻骨，所以古生物学家认为嵌齿象类拥有类似现代象的鼻子。

嵌齿象科起源于埃及法尤姆渐新世的象型动物 ，善于迁移, 在早中新世迁移到了欧亚大陆，在中中新世到达美洲。

嵌齿象科的分类系统还不是很明确，所以有几个属有可能是并系群。Gnathabelodon这个属通常被分类在Gnathabelodontidae这个科里面；而Archaeobelodon、Protanancus、Amebelodon、铲齿象（Platybelodon）与Serbelodon这几个属有时会被分类到Amebelodontidae这个科。

Gomphotheres are any members of the diverse, extinct taxonomic family Gomphotheriidae. Gomphotheres were superficially elephant-like proboscideans. They were widespread in North America during the Miocene and Pliocene epochs, 12–1.6 million years ago. Some lived in parts of Eurasia, Beringia, and following the Great American Interchange, South America. Beginning about 5 million years ago, they were gradually replaced by modern elephants, but the last two South American species, in the genus Cuvieronius, did not finally become extinct until possibly as recently as 9,100 BP, and Stegomastodon remains have been dated as recently as 6,060 BP in the Valle del Magdalena, Colombia. Gomphotheres also survived in Mexico and Central America until the end of the Pleistocene.