GN is often caused by antigen-antibody complexes depositing in the glomerular tissue.

肾小球肾炎通常是由于抗原-抗体复合物沉积在肾小球组织。

The rate at which this filtration takes place is known as glomerular filtration rate or GFR.

滤过的速率称为肾小球滤过率，或GFR。

In chronic kidney disease, the falling glomerular filtration rate leads to more and more renin secretion which leads to hypertension.

慢性肾病中，GFR降低，导致更多肾素分泌，进而引发高血压。

Finally the diagnosis of chronic kidney disease comes down to looking at changes in the glomerular filtration rate over time.

慢性肾病的诊断归根结底是基于肾小球滤过率随时间推移的变化。

These nutrients have carrier molecules that claim the glomerular molecule and release it back into the circulatory system.

这些营养物质的载体分子控制着肾小球分子，并将其释放回循环系统。

This reabsorption process allows water to pass from the glomerular filtrate back into the circulatory system.

这种再吸收过程使水从肾小球滤液进入循环系统。

One way these complexes can form is as a result of autoantibodies directly targeting the glomerular basement membrane.

这些复合物形成的途径之一是自身抗体直接攻击肾小球基膜。

For example, reduced blood flow to the kidneys, which are particularly susceptible, can cause glomerular damage leading to oliguria - very little urine - and proteinuria.

例如，血供不足最易先累及肾脏，可造成肾小球损伤，导致少尿和蛋白尿。

Also, other conditions like kidney hyperperfusion or increased perfusion of blood, as well as increased pressure in the glomerular capillaries have been linked to FSGS as well.

除此之外，肾高灌注或肾血流量增加等疾病以及肾毛细血管球内压力增高也与FSGS有关。

So when there is glomerular injury, red blood cells sneak into the urine —causing hematuria, which contributes to this being a type of nephritic syndrome.

因此当肾小球损伤时，红细胞溜进尿液，导致血尿，也是肾炎综合征的一个症状。