GABA is metabolized by the successive action of GABA transaminase (GABA-T) and succinic semialdehyde dehydrogenase (SSADH), to succinic acid, which is a substrate for the tricarboxylic acid cycle. GABA的降解主要由GABA转氨酶(GABA-T)催化,脱氨基生成琥珀酸半醛,再经琥珀酸半醛脱氢酶(SSADH)催化生成琥珀酸,进入三羧酸循环。
GABA的降解主要由GABA转氨酶(GABA-T)催化,脱氨基生成琥珀酸半醛,再经琥珀酸半醛脱氢酶(SSADH)催化生成琥珀酸,进入三羧酸循环。 GABA is metabolized by the successive action of GABA transaminase (GABA-T) and succinic semialdehyde dehydrogenase (SSADH), to succinic acid, which is a substrate for the tricarboxylic acid cycle.
Objective To study the changes of GABA receptor during the acute poisoning of unsymmetrical dimethylhydrazine(UDMH). 目的研究偏二甲基肼急性中毒时大鼠γ氨基丁酸(GABA)受体的变化。方法放射性配体结合试验。
At one time, we also studied the influence of GABA on veratridine-induced increase in the PKA activity and the influence of Allo on PKA activity. 同时,本实验也采用生化技术研究了GABA对veratridine增加PKA活性的影响,以及Allo对PKA活性的作用。
NG2-73 selectiely modulates receptors of the gamma-aminobutyric acid (GABA) neurotransmitter system and is one of seeral un partnered compounds in Neurogen's portfolio. NG2-73是GABA能神经受体的选择性调节剂,本项目暂无其他合作开发伙伴。
Objective: To investigate the changes of glutamate (Glu) and gamma-amino butyric acid (GABA) contents in rat brain induced by chronic ethanol treatment and study the protective effects of piracetam. 采用高效液相色谱电化学检测法分别测定大鼠小脑、大脑皮层、海马和丘脑中的谷氨酸及γ-氨基丁酸含量。
gamma-Aminobutyric acid (γ-Aminobutyric acid) /ˈɡæməəˈmiːnoʊbjuːˈtɪrᵻkˈæsᵻd/ (also called GABA/ˈɡæbə/ for short) is the chief inhibitory neurotransmitter in the mammalian central nervous system. It plays the principal role in reducing neuronal excitability throughout the nervous system. In humans, GABA is also directly responsible for the regulation of muscle tone.