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单词 Foldamers
释义

Foldamers

英语百科

Foldamer

Crystal structure of a foldamer reported by Lehn and coworkers in Helv. Chim. Acta.,  2003, 86, 1598-1624.[1]
Dynamic view of an alpha-beta foldamer
Folding and Coordination of an Oligopyrrole

In chemistry, a foldamer is a discrete chain molecule or oligomer that folds into a conformationally ordered state in solution. They are artificial molecules that mimic the ability of proteins, nucleic acids, and polysaccharides to fold into well-defined conformations, such as helices and β-sheets. The structure of a foldamer is stabilized by noncovalent interactions between nonadjacent monomers. Foldamers are studied with the main goal of designing large molecules with predictable structures. The study of foldamers is related to the themes of molecular self-assembly, molecular recognition, and host-guest chemistry.

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