脂肪酸合酶 Fatty acid synthase
（重定向自Fatty acid synthetase）
![](/Images/godic/202501/12/Protein_FASN_PDB_1xkt2007.png")
![](/Images/godic/202501/12/PBB_GE_FASN_212218_s_at_tn2007.png")
![](/Images/godic/202501/12/PBB_GE_FASN_217006_x_at_tn2007.png")
脂肪酸合酶（英语：Fatty acid synthase）是一个具有多种功能的酶系统，在哺乳动物中，其分子量高达272kDa。在脂肪酸合酶中，底物和中间产物分子在各个功能结构域（可以位于同一酶分子，也可以位于不同酶分子）中传递直到完成脂肪酸的整个合成过程。
Fatty acid synthetase
中文百科
英语百科
Fatty acid synthase 脂肪酸合酶
（重定向自Fatty acid synthetase）
![FAS revised model with positions of polypeptides, three catalytic domains and their corresponding reactions, visualization by Kosi Gramatikoff. Note that FAS is only active as a homodimer rather than the monomer pictured.](/Images/godic/202501/12/FASmodel22007.jpg")
Fatty acid synthase (FAS) is an enzyme that in humans is encoded by the FASN gene.
Fatty acid synthase is a multi-enzyme protein that catalyzes fatty acid synthesis. It is not a single enzyme but a whole enzymatic system composed of two identical 272 kDa multifunctional polypeptides, in which substrates are handed from one functional domain to the next.
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