Alpha effect

The alpha effect refers to the increased nucleophilicity of a molecule due to the presence of an adjacent (alpha) atom with lone pair electrons. The molecule does not necessarily exhibit increased basicity compared with a similar molecule without the adjacent, electron donating atom. The effect is well established with many theories to explain the effect but without a clear winner.

单词	Alpha Effect
释义	Alpha Effect 英语百科 Alpha effect The alpha effect refers to the increased nucleophilicity of a molecule due to the presence of an adjacent (alpha) atom with lone pair electrons. The molecule does not necessarily exhibit increased basicity compared with a similar molecule without the adjacent, electron donating atom. The effect is well established with many theories to explain the effect but without a clear winner.
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Alpha Effect

Alpha effect