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单词 Epalrestat
释义

Epalrestat

英语例句库

The synthesis of epalrestat,an aldose reductase inhibitor, was improved. The yield of its intermediate 3-carboxymethyl rhodanine was raised to 76.4%.

对醛搪还原酶抑制剂依帕司他的合成工艺作了改进,使中间体绕丹宁乙酸的收率提高到76.4%。

英语百科

Epalrestat

Epalrestat is a noncompetitive and reversible aldose reductase inhibitor used for the treatment of diabetic neuropathy, which is one of the most common long-term complications in patients with diabetes mellitus. It is well tolerated, with the most commonly reported adverse effects being gastrointestinal issues such as nausea and vomiting, as well as increases in certain liver enzymes.

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