Edrecolomab

Edrecolomab (MAb17-1A, trade name Panorex) is a mouse-derived monoclonal antibody targeting the cell-surface glycoprotein EpCAM (17-1A), which is expressed on epithelial tissues and on various carcinomas.

Preliminary studies had shown promise of a possible use in patients with stage III colorectal carcinoma (with metastasis to the lymph nodes). However, when put to a phase III study (2,761 patients) it did not provide any benefit when compared to conventional chemotherapeutic agents. No effect has been demonstrated for stage II (locally advanced cancer without spread to the lymph nodes) colon cancer.

单词	Edrecolomab
释义	Edrecolomab 英语百科 Edrecolomab Edrecolomab (MAb17-1A, trade name Panorex) is a mouse-derived monoclonal antibody targeting the cell-surface glycoprotein EpCAM (17-1A), which is expressed on epithelial tissues and on various carcinomas. Preliminary studies had shown promise of a possible use in patients with stage III colorectal carcinoma (with metastasis to the lymph nodes). However, when put to a phase III study (2,761 patients) it did not provide any benefit when compared to conventional chemotherapeutic agents. No effect has been demonstrated for stage II (locally advanced cancer without spread to the lymph nodes) colon cancer.
随便看	sclerynchyme sclerythrin scletotin Sclex scley SCLF SCLIGFET sclinder sclirosis SCLK sclks SCLM SCLN sclomina erinacea sclondre sclopetaria sclopetaria retinitis sclopette SC. L.P. SCLP Sc.L.P. SCL protein SCLR sclreid sclrometer