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单词 Dubin johnson syndrome
释义

Dubin johnson syndrome

英语百科

Dubin–Johnson syndrome

(重定向自Dubin johnson syndrome)
Dubin–Johnson syndrome has an autosomal recessive pattern of inheritance.

Dubin–Johnson syndrome (DJS) is a rare, autosomal recessive, benign disorder that causes an isolated increase of conjugated bilirubin in the serum. Classically, the condition causes a black liver due to the deposition of a pigment similar to melanin. This condition is associated with a defect in the ability of hepatocytes to secrete conjugated bilirubin into the bile, and is similar to Rotor syndrome. It is usually asymptomatic, but may be diagnosed in early infancy based on laboratory tests. No treatment is usually needed.

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