METHODS: The target compound was prepared by the bromination and amination reaction.

方法: 用溴代及胺化反应合成了四甲基吡嗪衍生物.

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Methods: The target compound was prepared through a four - step reaction from 4 - bromophenol .

方法以 4- 溴苯酚为原料,经4步反应制得目标化合物阿达帕林.

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METHODS: The target compound was synthesized from N - benzyl protected aminoacetophenone through hydrogenation, benzoylation and reduction.

方法: 以氮 - 苄基保护胺基酮为原料,经氢化, 苯甲酰化,还原三步合成双苯甲酰沙丁胺醇酯.

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Methods: The target compound was synthesized through bromination and thioetherification from 4 - methoxyacetophenone as a starting material.

方法以3-甲氧基苯硫酚和对甲氧基 - 苯乙酮为原料经溴化、烃基化、环合重排排制得目标产物.

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The target compound was synthesized via 6 steps from chloroacetyl chloride in 27.7 % overall yield.

以氯乙酰氯为原料,经6步反应合成目标化合物,总收率27.7%.

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