Simvastatin may effectively attenuate DN progression through down - regulating the expression of TGF - ? ? via p 38 MAPK.

斯伐他汀可能通过抑制p38MAPK磷酸化而减少TGF - β的蛋白表达.

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Objective To investigate the influences of simvastatin on carotid artery Intima - media thickness ( IMT ) and carotid atherosclerotic plaque.

目的探讨辛伐他汀对颈动脉内膜-中膜厚度及颈动脉粥样硬化斑块的影响.

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Both simvastatin and CDPC can relieve the damages of the brain in rats HIBD.

辛伐他汀和胞二磷胆碱可减轻新生大鼠HIBD后脑组织损害.

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Methods: Simvastatin was synthesized from lovastatin via acetylization, methylation, hydrolytic decomposition and cyclization reactions.

方法: 以洛伐他汀为原料,通过酰化 、 甲基化 、 水解、环合等反应合成了辛伐他汀.

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OBJECTIVE To prepare sustained - release dropping pills of Simvastatin and optimize its preparation technology.

目的制备辛伐他汀缓释滴丸并优化其制备工艺.

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CONCLUSION Early Simvastatin treatment effectively improves the cardiac function in ACS patients in a dose - dependent manner.

结论早期大剂量辛伐他汀干预能安全有效地改善ACS患者的心功能,降低心律失常的发生率,且呈剂量依赖性.

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