drug-discovery

Peptide library is one of the important techniques of combinatorial chemistry widely used for drug discovery.

TMC207 was discovered using an old method of drug discovery that has not been used in the last 40 years.

New candidate drug molecules that are advanced into preclinical testing by the research arm of a drug discovery company or organization.

Moreover, these views do not reflect those of Elsevier, Drug Discovery Today or its editorial team.

Industrial research is now facing the challenge of translating this information efficiently into drug discovery.

Our portfolio includes companies focusing on biopharmaceuticals and drug discovery, as well as medical devices and diagnostics.

Among them, mass spectrometry has grown to be a front-line tool throughout drug discovery.

If that came to pass, this small step on the journey of drug discovery might come to be seen, in retrospect, as a giant leap.

I look forward to the time when this ability is in widespread use to hasten drug discovery and to support an array of other applications.

Positron emission tomography (PET) is a molecular imaging technique with particularly broad application in drug discovery and development.

PPD is a leading global contract research organization providing drug discovery, development and lifecycle management services.

Despite this, most drug discovery efforts search for drugs that are composed of a single chemical entity.

proteomics and metabolomics, scientists are also using chemical genomics, an approach that reverses the standard drug discovery process.

Simple, direct and automation-ready procedures for measuring hemoglobin concentration are becoming popular in Research and Drug Discovery.

Drug discovery and development efforts are fragmented across the continent.

Shi says he earns less in China than at Princeton, where he ran a structural biology lab and helped found a drug-discovery company.

During the long period of drug research, a lot of drug screening models come forth, which played active roles in drug discovery.

"This broadens the notion of what drugs can do, and has wide-reaching implications for future drug discovery for many different disorders. "

Drug screening model is one of the most important conditions in drug discovery and testing the mechanism of drugs' effects.

These results have implications for the patenting strategies of small biotech companies involved in drug discovery.

The approaches and concepts that encompass combinatorial chemistry represent a paradigm shift in drug discovery and basic research.

High-throughput protein X-ray crystallography offers an unprecedented opportunity to facilitate drug discovery.

The drug development programme in Edinburgh is supported by a Seeding Drug Discovery award from the Wellcome Trust.

Structural modification could be valuable for natural product-based drug discovery.

But AstraZeneca has also set up a research centre outside Shanghai crammed with advanced drug-discovery tools.

Network pharmacology has been one of the new strategies for new drug discovery based on single-target drug research in recent years.

Recent reviews in Drug Discovery Today have concentrated on screening by docking and by pharmacophore searching.

Our laboratories are equipped with modern instruments and platforms for cutting-edge drug discovery research.

ta. identifies and implement integrated informatics solutions to support drug discovery.

She warned: "The demise of antibacterial drug discovery brings the spectre of untreatable infections. "

The Alzheimer's Society has launched the Drug Discovery programme, which it says could lead to new treatments for dementia within a decade.

Because of its simplicity and stable results, this method can give implication for the drug discovery of other pathogenic strains.

The project is stimulating biological research, which in turn is the driving force in drug discovery today.

Each chapter provides the critical facts needed to initiate a drug discovery effort in that particular area.

Combining bioinformatics with drug discovery is a promising method to tackle this issue.

This review discusses the use of genomic information in the rapid identification of target genes for antimicrobial drug discovery.

Fragment-based drug discovery (FBDD) represents a logical and efficient approach to lead discovery and optimisation.

Natural products are one of the most important sources of the lead compounds in drug discovery.

Drug Discovery : high-throughput screen for toxic and anticancer drugs.

This research is also supported by a Seeding Drug Discovery Award from the Wellcome Trust.

How can modern drug discovery methods enhance the value of African traditional medicines, asks South African drug expert Kelly Chibale.

It is for this reason that proteases have become popular targets for drug discovery.

The current use of metrics-driven approaches to improve the productivity of pharmaceutical drug discovery will fail.

Wainwright is also a researcher in the Center for Drug Discovery and Chemical Biology at Feinberg.

Lilly calls its new program the Phenotypic Drug Discovery Initiative, or PD2 (pronounced PD-squared).

Bioinformatics techniques are therefore certain to play an increasingly important role in drug discovery.

Aptamers could be utilized in target validation, new drug discovery and as delivery vehicles for other drug molecules.

In this article we will discuss recent progress and challenges in the field in this highly competitive area of drug discovery.

Powerful new technologies such as high-throughput screening and combinatorial chemistry are revolutionizing drug discovery.

The finding may open up an avenue of drug discovery for the disease.

In addition to financial support specific know-how on target validation and drug discovery is provided.

This process of new drug discovery requires a team effort.

The drug discovery initiative has a deadline of 11 September for applications.

Cell model for drug screening is the first step for drug discovery.

Another use of simulation in drug discovery is screening drugs for multiple actions.

Could a new business model revive drug discovery?

The result is that the chemistry of traditional medicines is rarely sampled in modern drug discovery efforts.

Drugs giants such as Roche and Merck are also routinely using microarrays in their drug-discovery processes.

He rejects any suggestion that drug discovery was easier in the past.

The findings could open up new areas for drug discovery, says the study published in Science.

"We can crack the problem of patented drug discovery in India at a much lower cost" than in the West, predicted Mr.

This year, for example, Pfizer announced a major investment in autism drug discovery which includes a dedicated autism neuroscience unit.

Paul Wyatt at the Drug Discovery for Tropical Diseases program at the University of Dundee led the study.

According to Peterson, small molecule inhibitors such as IPA-3, are promising tools for drug discovery.

Screening of Combinatorial Libraries and Its Application in Drug Discovery

Microbial biopharmaceuticals and antibody-based drugs-promising for new drug discovery and development

Drug metabolism and pharmacokinetics: applications in drug discovery and development

Combinatorial chemistry and its application to drug discovery

Overcoming Challenges in Antibacterial Drug Discovery and Development

Application of Diversity-oriented Synthesis and Forward-synthesis Analysis in Drug Discovery

Irrespective of the process of novel drug discovery, all drugs must undergo a lengthy process of preclinical and clinical review;

Advanced Glycation End Products and Strategies for the Anti-athrogenic Drug Discovery

Chemical Proteomics and Its Application to Drug Discovery

Virtual Screening Opportunities in Drug Discovery in Europe

A novel strategy of anticancer drug discovery: cell phenotype profiling and chemical genomics

Perspectives in Drug Discovery and Development Technologies

The Application of Structure-based Combinatorial Library Design in Drug Discovery

The international symposium for medicinal chemistry and drug discovery

Accelerating Drug Discovery And Design (Drugs and the Pharmaceutical Sciences)

Pharmacokinetic Challenges in Drug Discovery

Application of Biochip Technology in Drug Discovery and Development

Drug Discovery; Categories of Psychiatric Disease

Model Organisms in Drug Discovery and Development: An Industry Analysis

Application of Combinatorial Chemistry in New Drug Discovery

Drug discovery based on pharmacological interference with glycometabolism

Soil metagenomics and its application for new drug discovery

Exploiting Chemical Diversity For Drug Discovery

Recent Patents on Cardiovascular Drug Discovery

Chemoinformatics and the openness of drug discovery research

Role of Drug Metabolizing Enzymes in Drug Discovery and Development

Role of Drug Metabolizing Enzymes in Drug Discovery and Development

e-Solution for Integrative Drug Discovery and Development

Cell signal transduction and novel anti-cancer drug discovery

Application of Multi-Agent Based Load Balancing in Drug Discovery Grid

Progress on applying of bioinformatics in drug discovery

Application of Gene Chip in Antimicrobial Drug Discovery

Secondary metabolic pathway genes and new drug discovery

High-throughput Virtual Screening: A New Strategy in Drug Discovery

Structure-Guided Drug Design Rediscovering the Importance of Drug Structure for Drug Discovery

The important role of biochemoinformatics in drug discovery and development

Trends and Emerging Technologies in Drug Discovery

Drug Discovery: From Bedside To Wall Street: From Bedside To Wall Street

RNA as a target for anti-infective drug discovery

Roles of Glycosidase in Drug Discovery and Development

Basic Research and Engineering for Drug Discovery

A new method for drug discovery -- high throughput screening

Application of Genechip Technology in Drug Discovery and Development

New Drug Discovery and Development of Traditional Chinese Medicines

Recent Patents on Anti-Infective Drug Discovery

Handbook Of Assay Development In Drug Discovery

Drug Discovery for Nervous System Diseases

Drug discovery & Drug screening in Vitro or Vivo Studies

Biochips in Drug Discovery in Europe

Post Genomics Drug Discovery and Research

Thoughts on The New Drug Discovery and Development

The Usage of Bioinformatics in Gene and Drug Discovery

Virtual screening in drug discovery

Chemical Genetics in Drug Discovery

Target validation in drug discovery

Recent Patents on Anti-Cancer Drug Discovery

random screening in drug discovery

2003 Reducing the Attrition Rate in Drug Discovery Conference

Impacts of Modern Biology on Drug Discovery

Licensing IP to with western drug discovery

Progress in Asthma Drug Discovery

Modern methods in drug discovery

Recent Patents on CNS Drug Discovery

Novel Targets in Drug Discovery

Modern Method of Drug Discovery

Drug discovery and protein science, DDPS

21St Century Drug Discovery-From gene to Drug

Current status of drug discovery and development in China

Drug Discovery and Development Based on Biacore S51