cytotoxic

The taxanes, which are among the most promising cytotoxic agents in clinical use have considerable activity in a number of tumor types.

The authors give an account of the basic concept and classification of cytotoxic drugs.

Nitric oxide as a cytotoxic factor may be partial to kill sperm and the sperm suppression activity due to infertility .

Defensins are small, cystin-rich, antimicrobial and cytotoxic peptides, which have been found in a large range of living organisms.

A frequent problem encountered with conventional chemotherapy is the lack of appreciable water solubility exhibited by the cytotoxic agent.

Adriamycin is frequently used in combination chemotherapy regiments with other cytotoxic drugs.

A cytotoxic substance is preferably bound to the anti-HB-EGF antibody of the present invention.

These T cells are sometimes referred to as cytotoxic T cells.

However, mechanistic considerations suggest that antioxidants might reduce the effects of conventional cytotoxic therapies.

Antibody-directed enzyme prodrug therapy aims to restrict the action of a cytotoxic drug to cancer sites.

OBJECTIVES Monitoring the concentration of the cytotoxic drugs in drug configured room in various work periods and areas.

Displays cytostatic and cytotoxic activity. Inhibitor of EGFR kinase. Shows antiangiogenic activity.

Thus, a hypercalcemia-induced cytotoxic effect in the central nervous system may play an important role in neuropsychiatric manifestations.

However, antibodies that bind these targets are often, by themselves, non-cytotoxic.

Cytotoxic T cells, after sensitization by antigen, are effector cells, especially important in antiviral immunity.

Whereas both exert their cytotoxic effect by incorporating into DNA, they have substantially different systemic and cellular pharmacology.

The ovaries are very sensitive to cytotoxic treatment, especially to alkylating agents.

It is practicable to use Cytotoxic T Lymphocyte of Effusion-Associated Lymphocytes for studying tumor-induced immunosuppression.

Results: Times of contacting cytotoxic drugs was positively correlated with damaging degrees of health of nursing staffs.

The cytotoxic and cytogenetic effect of sodium arsenite and sodium arsenate on Chinese hamster ovary ( CHO ) cells is reported.

ATLS results when cytotoxic agents lyse, or lacerate, outer plasma membranes of numerous cancerous cells.

The rationale for developing anti-HIV vaccines that stimulate cytotoxic T-lymphocyte responses is given.

Otherwise, EBV is kept in check by the surveillance activity of cytotoxic T lymphocytes and NK cells.

Objective: To probe the cytotoxic effect of paclitaxel on human osteosarcoma cell line SOSP-9607 and its mechanism.

Its cytotoxic effects and dosage-dependent relationship on growth of tumor cells were examined by MTT assay.

Since the development of the first cytotoxic agents, synthetic organic chemistry has advanced enormously.

Conclusion Monoclonal antibody against vascular endothelial cells can be made in hepatocarcinoma site and has cytotoxic effect in vitro.

The hypoxic environment of tumours is heterogeneous, both spatially and temporally, and can change in response to cytotoxic therapy.

Normally dendritic cells show an invader to T cells which produce cytotoxic T cells to destroy it.

Conclusions: NO cytotoxic effect was detected in HBO treatment.

Objective To investigate the mechanism of cytotoxic efficacy of CD4 T cells in B cell non-Hodgkin s lymphoma(NHL) .

ObjectiveTo investigate the cytotoxic effect of multi-walled carbon nanotubes(MWCNTs)on human liver L02 cells and its relevant mechanism.

In our limited series of cases, steroid in combination with cytotoxic therapy was effective.

Killer or cytotoxic T cells destroy infected and foreign cells.

They are responsible for cytotoxic T lymphocyte (CTL) production.

Both helper and cytotoxic T cells are stimulated by platelets.

Natural cytotoxic activity in the umbilical blood was estimated in 52 healthy newborns.

The former are brought about by T lymphocytes termed cytotoxic T cells, that seek out and kill virally -infected host cells or cancer cells.

Results: 5 FU both inhibited proliferation of HUVEC in vitro and suppressed angiogenesis of CAM in vivo at none cytotoxic doses.

It plays a key role in the pathogenesis of HN that cytotoxic CD8 T cells eliminate central nevus.

New cytotoxic drugs, such as taxanes and topoisomerase inhibitor etc, and new regimens are focus researches for medical treatment.

The mechanism by which chronic-phase CML cells become resistant to conventional cytotoxic drugs, such as hydroxyurea, is unknown.

Both "helper" (CD4) and "cytotoxic" (CD8) T-cell classes have been described.

In addition, it is known that high concentrations of methylglyoxal are really cytotoxic.

For mice, Wild Ply has an immune protection effect. To human, it is not appropriate because of cytotoxic.

Because tumor response to cytotoxic chemotherapy has been poor, chemotherapy is used only for palliation.

Add the serums to GMC to do the cytotoxic experiment.

These are the classical cytotoxic drugs. But what is the optimal dose for such drugs?

In the same time, cytotoxic activity of NK cells was detected.

5d cytotoxic levels dropped by 4 to 2.

Research, development, production in the body, mainly to study and produce sterile drugs, health care products, such as cytotoxic drugs.

Nowhere is this truer than for oncology, which previously was dominated by cytotoxic drugs.

OBJECTIVE: To study the cytotoxic effect in vitro and antitumor effect in vivo of hypericum chinense.

Study of the cytotoxic mechanism about palmitic acid on vascular endothelial cells

The Cytotoxic Effects of the Adriamycin Magnetic Albumin Microspheres Combined with External Magnetic Fields on the Malignant Tumor Cells

poisoning and pollution through the release of pharmaceutical products, in particular, antibiotics and cytotoxic drugs;

Synthesis, characterization and cytotoxic activity of a new oxaliplatin analog

The preparation of liposome of phenylalanine ammonia-lyase and its cytotoxic activity assay on leukemia cells

In vitro cytotoxic study of a new dentin bonding agents

The direct cytotoxic effect of dendritic cells from human peripheral blood and cord blood upon the cervical carcinoma cells lines

Experimental study on cytotoxic effects of arsenic trioxide in combination with chemotherapeutic drugs on acute leukemia cells

Intravesical instillation of cytotoxic T-lymphocytes induced by soluble tumor antigen in the prophylaxis of recurrence of bladder cancer

Observation on rat lymphocyte proliferation and cytotoxic activity in vitro after acute myocardial infarction

Security of Dual Cancer-specific Targeting Vector and Its Cytotoxic Effect when Harbored

Detection of Heterogeneous Type II Collagen Transplantation Mediated Cytotoxic Response In Vitro;

Study on the inhibition of 11 Cytotoxic Drugs on the Ovarian Cancer Cells and its Relationship with the Effects on the Nucleated Cells

Screening of Cytotoxic Actinomycetes Isolated from Mangrove Area and Primary Study About Activity Substance

The application of preventive control in the management of prevention of the effusion of cytotoxic drugs from vein

Investigation of the practice and knowledge on safe handing of cytotoxic drugs of oncology nurses in Shanghai

Studies of cytotoxin from guangxi cobra venom on its purification and cytotoxic effects on the nasopharyngeal and other cancer cells

Cytotoxic Influence of Pentoxifylline on Pyrimidine Antagonist

Adopting centralized management in compounding cytotoxic drugs

Extravasation of Cytotoxic Agents Compendium for Prevention and Management

The cytotoxic effect, cell cycle perturbations and apoptosis by gemcitabine in human bladder cancer lines

Influence of rat serum containing Radix Dipsaci on the proliferation of osteoblasts as well as its cytotoxic detection

Isolation and Cytotoxic Activity Evaluation of Microorganisms from Mangrove in Hainan

Cytotoxic effect and radiation enhancement of docetaxel in uterine cervical carcinoma cell line Hela

The cytotoxic effect, cell cycle perturbations and apoptosis of paclitaxel in human bladder cancer lines

Influence of Different Infective Dose of REV on Immunity Responses and Cytotoxic Activity in Chickens

Cytotoxic evaluation of polymeric calcium phosphate bone cements

Cytotoxic effect of methylglyoxal on cultured human vascular endothelial cells

Predictive Value of In Vitro MTT Assay Chemosensitivity Test of Cytotoxic Drug Activity in Cervical Cancer

Cytotoxic effect of cisplatin with proteasome inhibitor on osteosarcoma cells

Expression of the virulence gene mviN of Leptospira interrogans serovar Lai and its cytotoxic effect

Significance of activated cytotoxic cell in lymphoma by tissue microarray

The cytotoxic effects of extracts from dominant indoor airborne fungal culture

Cytotoxic Activity of Dendritic Cells Vaccine from Cord Blood on Human Hepatoma Cells in vitro

Relationship of apoptosis to cytotoxic lymphocytes and LMP-1 expression in nasopharyngeal carcinoma

Study on the relationship between recurrent spontaneous abortion and the cytotoxic effect of NK cells

Detection of activated cytotoxic cells in lymphoma by tissue microarray

A survey of self- protection awareness of nurses contacting with cytotoxic drugs

Cytotoxic effect of oncolytic virus combined with mitomycin against human bladder cancer cells in vitro and in vivo

Research on the Cytotoxic and Genotoxic Effects of Rare-earth Element Holmium to Vicia faba

A primary study on antimicrobial and cytotoxic activity of marine bacteria

The Direct Cytotoxic Effect of Activated Dendritic Cell Derived from Cord Blood on Tumor Cells

Study on Systematics of the 26 Marine Actinomycetes Having Cytotoxic Activity

Study on Cytotoxic Effect and Antitumor Effect of Paclitaxel Liposome

Cytotoxic effects of granulysin on Candida albicans

Cytotoxic effect of oxysterols on cultured rat aortic smooth muscle cells

Studies on Cytotoxic Constituents from Sophora tonkinensis

Induction of Cytotoxic Drugs to in situ Cell Apoptosis in Acute Leukemias

Cytotoxic effects of gastric cancer cell-DC fusion vaccines

Study on the cytotoxic activity of NK-92 cells against human nasopharyngeal carcinoma cells in vitro

Cytotoxic effects of bile acids on human pancreatic cancer cell

ADDC antibody dependent cytotoxic cell

The cytotoxic effect of cadmium on human matured dendritic cells

Study on the cytotoxic activity of irradiated NK-92 cells against human ovarian carcinoma

Organic Solvents Cytotoxic Effect on Cancer Cell

IL-2 gene therapy enhances cytotoxic effect of E. Coli. Cytosine deaminase gene for colon cancer

The Determination of 4 Parameters Influencing the NK Cytotoxic Index

The Cytotoxic Effect of Thermochemotherapy on Carcinoma Cell Line

Cytotoxic effect of adriamycin hyperthermia on rabbit carcinoma cell line VX-2 in vitro

The role of nitric oxide in the cytotoxic effect of macrophages

Cytotoxic effects of ibotenic acid on hippocampal neurons in rats

Differential expression of perforin in cytotoxic lymphocytes in HIV infected individuals in China

Advances in the Research of Cytotoxic T-Lymphocyte Antigen-4

In vitro cytotoxic study of five kinds of dentin adhesive agents

Pharmacy cytotoxic drug reconstitution services and role of oncology pharmacists in Hong Kong