dna repair

That activates the cell's DNA repair mechanisms, but if the damage is too extensive to be repaired, the cell undergoes programmed suicide.

Several proteins, which have diverse functions and are not known to have roles in DNA repair, also associate with damaged DNA.

Such tumors display microsatellite instability, an acquired genetic characteristic that indicates defects in DNA-repair machinery.

Levels of a DNA repair protein naturally rise in the morning and fall later in the day, which may make exposure to UV safest early.

Highly conserved DNA-repair and cell-cycle checkpoint pathways allow cells to deal with both endogenous and exogenous sources of DNA damage.

Chromatin modifications are important for all cellular processes that involve DNA, including transcription, replication and DNA repair.

Radiation destroys DNA but this creature has a spare copies of the most vital bits, as well as speedy DNA repair mechanisms.

Recent research revealed that sumoylation is involved in mitochondrial fission, DNA repair, the ion channel control and circadian clock.

The DNA repair capability of individual is close to the polymorphic genotypes.

A second cluster of Ashkenazi lipid storage disorders might stimulate neuron proliferation in the DNA repair genes.

Eukaryotic cells employ multiple strategies of checkpoint signaling and DNA repair mechanisms to monitor and repair damaged DNA.

They exposed the cells to ionizing radiation and analyzed DNA repair responses as telomeres became progressively shorter.

Similarly, several genes that encode proteins involved in DNA repair were also expressed at lower levels in former and current smokers.

"One explanation may be that these species have, for whatever reason, less capable DNA repair mechanisms, " said Professor Mousseau.

Many studies on DNA repair and DNA metabolism confirm a relationship between longevity and efficiency of maintenance.

PCNA also plays an important role in the DNA repair of neuron, gliocyte proliferation, and cell apoptosis after cerebral ischemia.

Defects in MYH, a DNA repair enzyme, are present and linked to colorectal cancer in patients with adenomatous polyposis coli.

Scientists would alter these cells by inserting genes or activating the cells' DNA - repair mechanisms.

Covalent histone modifications and ATP-dependent chromatin remodeling play important roles in the process of DNA repair.

To explore the relationship between polymorphisms of DNA repair gene XRCC1 and susceptibility to radiation injury.

There is an intimate relationship between ER mediated transcription and DNA repair.

One is that the microwaves create cellular stress in the brain, and that the stress jump-starts DNA repair mechanisms in the brain.

In this article, we will review the progress of several basic ways of the relationship of DNA repair gene with liver cancer.

To protect cell membranes and DNA repair the damage, inhibit cancer health effects.

To investigate the relationship between polymorphisms of DNA repair gene XRCC3 and the risk and clinical outcome of bladder cancer.

In experiments on mice with lung tumours the researchers showed that blocking a molecule called Cdk1 also stopped DNA repair.

Scientists had shown previously that DNA repair was much less efficient when FANCI and FANCD2 lack the single ubiquitin.

Some DNA repair mechanism can even induce mutagenesis so that the offspring may adapt to the new environment.

Radiotherapy might thus be made more effective against them by dosing them with existing drugs that inhibit DNA repair.

This led them to the functional experiments that established its role in DNA repair.

DNA main replicative polymerases are also involved in many DNA repair processes.

Thus SIRT6 may be a master regulator that coordinates stress and DNA repair activities, according to Gorbunova.

Defects in DNA repair (eg, xeroderma pigmentosum) commonly result in skin cancer.

The protein encoded by BRCA1 is involved in DNA repair.

It leads to less DNA repair and more mutations.

But what's unique about it is that it's doing DNA repair below freezing.

Investigation of DNA Repair Gene Expression Pattern of Radiation-Induced Malignant Transformation of Human Bronchial Epithelial Cells

Study on polymorphisms in metabolic enzyme genes, DNA repair genes and individual susceptibility to hepatocellular carcinoma

Study on the DNA repair ability and transformation function of lymphocytes in patients with active pulmonary tuberculosis

Effect of c-fos antisense oligonucleotide on DNA repair gene expression around hematoma in intracerebral hemorrhage

Single nucleotide polymorphism of DNA repair gene XPD and genetic susceptibility of biliary tract cancers

Analysis of DNA-repair genes in the gene expression profiles associated with malignant progression of human gliomas

Detection of the DNA Repair Capacity of Cancer Patients after Bleomycin Exposure

Promoter Hypermethylation of DNA Repair Gene MGMT in Esophageal Squamous Cell Carcinoma

Determination of DNA damage induced by AGEs and DNA repair with pyridoxamine in mice spleen lymphocytes in vitro

A Review of Research on the Relationship between Polymorphisms of DNA Repair Genes and Lung Cancer Susceptibility

Hypermethylation of CpG island in promoter region of DNA repair gene MGMT in esophageal carcinoma

Changes in PCNA, a protein involved in DNA repair, in the neurons following focal cerebral ischemia in age rats

The single nucleotide polymorphism in the promotor of DNA repair gene XPA and in association with the risk of lung cancer

Research Progress of DNA Repair and Resistance to Platinum-based Chemotherapy

Effects of in vivo exposure to low doses of different radiator nuclides on DNA repair capability

The relations between polymorphisms of DNA repair genes and bladder cancer

Assessment of DNA repair capacity in cancer patients with bleomycin test and UVC test

standard practice for the in vivo rat hepatocyte dna repair assay

Regulation of ATP on DNA Repair and Cell Apoptosis Induced by Irradiation

Research Progress on DNA Repair Mechanisms of Deinococcus Radiodurans

An important method to comment on DNA damage and DNA repair ability: Comet assay

GAMMA RADIATION EFFECT ON DNA REPAIR SYNTHESIS IN LYMPHOCYTES

Progress of Enzyme in Mitochondrial DNA Repair System

Computational Analysis of Genes and Proteins related to Human Diseases and DNA repair

DNA repair and resistance of lung cancer to cisplatin

Damage of ionizing radiation and DNA repair gene

The influence of DNA repair ability on GPA mutation frequency and it's detection

Association of genetic polymorphisms in the DNA repair gene XPD with risk of lung and esophageal cancer in a Chinese population in Beijing

Association of the DNA repair gene genetic polymorphisms and risk of nasopharyngeal carcinoma in Sichuan Luzhou population

Effect of Fructus Lycii on DNA Repair Capacity in the Aged

Association of metabolic and DNA repair enzyme gene polymorphisms and DNA damage in coke-oven workers

Association of genetic polymorphism in the DNA repair gene XPD with risk of lung cancer in nonsmoking females