| 单词 | dna methylation |
| 释义 | 例句释义: 去氧核醣核酸甲基化,基因甲基化,甲基化现象 1. Researchers looked for - and found - a chemical change called DNA methylation in healthy tissue adjacent to breast tumors. 研究者寻找并发现了靠近肿瘤组织的健康组织中有“DNA甲基化”这种化学改变。 news.dxy.cn 2. Consistent with these important roles, a growing number of human diseases have been found to be associated with aberrant DNA methylation. 越来越多的人类疾病被发现同DNA甲基化的异常有关。 www.biooin.com 3. In malignant cell the pattern of DNA methylation, as well as the set of DNA methyltransferase activities, differs from that in normal cell. 在恶性肿瘤细胞中，DNA甲基化模式，以及一套DNA甲基转移酶活性不同于正常细胞。 chinapubmed.net 4. DNA methylation is one of the most common epigenetic events occurring in human genome and is implicated in cancer. DNA甲基化是人类基因组发生最为常见的一种表观遗传学事件，因而研究甲基化与肿瘤的关系成为当前分子生物学的热点之一。 www3.chkd.cnki.net 5. It can be thus suggested, that the plant cell contains at least two different, and probably, interdependent systems of DNA methylation. 因此能够建议，植物细胞包含至少两种不同，可能相互依赖的DNA甲基化系统。 chinapubmed.net 6. DNA methylation is a chemical modification made to DNA that plays an important role in dictating how DNA is read and interpreted by a cell. DNA甲基化是一个化学修饰，它在让细胞正确的解读DNA的过程中起着重要的作用。 news.dxy.cn 7. The work is one of several clues that DNA methylation affects the formation and maintenance of memories. 这项工作是DNA甲基化影响记忆形成和延续的线索之一。 news.dxy.cn 8. One of the best known epigenetic factors is DNA methylation, which is a major mechanism for regulation of gene expression. 表观因子中最著名的一个是DNA甲基化，它是基因表达调控的一个主要机制。 www.chinapubmed.net 9. Therefore, profiling DNA methylation across the genome is vital to understanding the influence of epigenetics. 因此，跨基因组的DNA甲基化谱对于理解表观遗传学的影响是极其重要的。 www.chinapubmed.net 10. DNA methylation is an important epigenetic modification which regulates a number of biological processes. DNA甲基化作为一种重要的表观遗传修饰，调节着机体许多生物学过程。 www.chemyq.com 1. Several epigenetic drugs targeting DNA methylation and histone deacetylation enzymes have been tested in clinical trials. 靶向DNA甲基化和组蛋白去乙酰化酶的几个表观药物已经在临床试验中被测试。 www.chinapubmed.net 2. DNA methylation is one of the most common epigenetic events in eukaryotic cell. DNA甲基化是真核细胞基因组最常见的一种表观遗传学修饰。 kns50.chkd.cnki.net 3. In plants, aberrant RNA signals direct DNA methylation to target sequences, sometimes appropriately and sometimes inappropriately. 在植物中，异常RNA信号有时适当的，有时不适当的指导了DNA甲基化成为靶序列。 chinapubmed.net 4. Aberrant DNA methylation is one of the major characteristics of tumor cells in addition to genetic and other epigenetic alterations. DNA甲基化的异常是肿瘤细胞的主要特征之一，此外还有遗传的和其他表观上的改变。 word.hcbus.com 5. However, there is such a diversity of DNA methylation profiling techniques that it can be challenging to select one. 但是，有如此多种多样的DNA甲基化谱技术，选择其一可能是有挑战性的。 www.chinapubmed.net 6. DNA methylation, catalyzed by methyltransferases, is a normal epigenetic DNA modification approach in eukaryotic cells. DNA甲基化由DNA甲基转移酶催化发生，是真核细胞DNA正常的表观遗传学修饰方式。 www3.chkd.cnki.net 7. Here, we review the advances in this field, meanwhile, function of DNA methylation in recombination suppression is being analysed briefly. 本文较全面综述了这一领域的进展，并对DNA甲基化在植物性染色体重组抑制形成过程中可能的作用进行了简要分析。 www.chinagene.cn 8. Many studies showed that DNA methylation is specific marker of NSCLC in its diagnosis, staging, treatment and prognosis. 研究显示，DNA甲基化是非小细胞肺癌（NSCLC）诊断、分期及治疗预后特异性较强的标识物。 www.chemyq.com 9. DNA methylation plays an important role in gene expression regulation during biological development and tissue differentiation in plants. DNA甲基化参与植物基因的表达调控，在植物的生长发育和组织分化中起着重要的作用。 www.showxiu.com 10. The analysis of DNA methylation in plasma will have the powerful potentiality that applicate to noninvasive prenatal diagnosis. 血浆DNA甲基化的分析进一步应用于无创性产前诊断具有可行性。 terms.shengwuquan.com 1. Differential histone modification marks of active versus repressed genes accompany these DNA methylation changes. 活化的差异组蛋白修饰标记物对抑制基因的改变伴随着这些DNA甲基化改变。 news.dxy.cn 2. Both DNA methylation and histone modification are involved in establishing patterns of gene repression during development. 这两个DNA甲基化和组蛋白修饰参与建立模式的发育过程中基因的镇压。 www.syyxw.com 3. DNA methylation is a major epigenetic modification and plays a crucial role in embryonic development and placentas'development. DNA甲基化是一种主要的表观遗传修饰，对于胚胎发育、胎盘及胎儿的生长具有重要作用。 www.fabiao.net 4. Thus, the DNA methylation is imposed on the transition between the active versus repressed transcription state for CD133 only in tumors. 这样，DNA甲基化发生于肿瘤中CD133的活化状态到抑制转录的过渡中。 news.dxy.cn 5. It stores information about the origin of the investigated sample and the experimental procedure, and contains the DNA methylation data. 它存储了有关研究样品来源信息和实验步骤信息，并包含了DNA甲基化数据。 www.chinapubmed.net 6. We present here a database for DNA methylation data that attempts to unify these results in a common resource. 这里我们提出了一个DNA甲基化数据库，它试图在一个公共资源中统一这些结果。 www.chinapubmed.net 7. In plants inhibition of DNA methylation is accompanied by the induction of seed storage and florescence genes. 在植物中，DNA甲基化的抑制伴随着种子贮藏和开花基因的诱导。 chinapubmed.net 8. In this review, we discuss some general themes in DNA methylation analysis and outline the basic principles of current key techniques. 在本综述中，我们讨论了一些DNA甲基化分析中常规的主题，并概述了当前关键技术的基本原理。 chinapubmed.net 9. DNA methylation has an important role in transcriptional regulation, togethering with histone modification and chromatin remodeling. DNA甲基化在基因转录过程中扮有重要角色，并与组蛋白修饰、染色质构型重塑共同参与转录调控。 dictsearch.appspot.com 10. DNA methylation is one of the most important and distinct forms of epigenetic modification. DNA甲基化是表观遗传修饰中一种最为重要的DNA修饰。 www.bing.com 1. In plants, DNA methylation is regulated by a complex interplay between several methylating and demethylating enzymes. 在植物中，DNA甲基化通过一些甲基化和去甲基化酶的一个复杂相互作用而被调节。 chinapubmed.net 2. DNA methylation contributes to the control of gene expression and plays an essential role in cellular physiology. DNA甲基化有助于基因表达的控制，并在细胞生理中起着一个关键的作用。 chinapubmed.net 3. Although researches in this area have been reported, but DNA methylation in the hybrid variations of inter-generational studys are rare. 虽然这方面的研究报道已有很多，但DNA甲基化在杂交世代间的变异规律的研究并不多见。 paper.pet2008.cn 4. The advent of microarray technology has provided new opportunities for high-throughput study on DNA methylation. 芯片技术的发展为高通量研究DNA甲基化提供了新的方法。 www.chinagene.cn 5. DNA methylation patterns are set up early in mammalian development and are then copied during the division of somatic cells. DNA甲基化模式是建立在早期哺乳动物的发展，然后会在体细胞分裂复制。 www.syyxw.com 6. According to many researches, the variation of DNA methylation can be transferred to the offspring by cell division. 许多研究发现DNA甲基化的变异能通过细胞的分裂传递给后代，为物种的变异和进化提供了机遇。 www.fabiao.net 7. Here, we present an in situ method for DNA methylation analysis, which has high sensitivity and good reproducibility. 这里，我们提出了一种原位方法用于DNA甲基化的分析，它具有高灵敏性和良好的可重复性。 chinapubmed.net 8. New techniques are making it easier to map DNA methylation patterns on a large scale and the results have already provided surprises. 新的技术让您更轻松地地图DNA甲基化模式进行大规模的结果已提供惊喜。 www.syyxw.com 9. DNA methylation is the unique natural covalent modification of vertebrate animals. DNA甲基化是脊椎动物DNA唯一的自然共价修饰方式。 www.chemyq.com 10. DNA methylation is a prominent epigenetic mark and extensively found within plant genomes. DNA甲基化是显著的表观遗传标记，并且大量发现于植物基因组中。 www.chinapubmed.net 1. Recent evidence indicates that DNA methylation is a promising biomarker for cancer. 研究显示DNA甲基化是一类潜力很大的肿瘤标志物。 kns50.chkd.cnki.net 2. In this review, we summarized the advances on DNA methylation for noninvasive cancer diagnosis. 本文对DNA甲基化在恶性肿瘤早期诊断的研究进展作一综述。 kns50.chkd.cnki.net 3. In plants and animals this DNA methylation is species-, tissue-, and organelle-specific. 在植物和动物中，这种DNA甲基化是物种，组织和器官特异的。 chinapubmed.net 4. The relationship between levels of DNA methylation and gene activity has been known for some time. 很久以前就知道DNA甲基化水平和基因活性间的关系。 chinapubmed.net 5. DNA methylation is a frequent change in epigenetics of leukemia. DNA甲基化是白血病表观遗传学改变中较常见的改变。 www.ceps.com.tw 6. It attempts to store all data about DNA methylation in a common source. 它试图以一种共同的来源存储有关DNA甲基化的所有数据。 www.chinapubmed.net 7. It take for S-adenosylmethionine as methyl donor. DNA methylation has essential roles in many plant life processes. DNA甲基化在植物的很多生命过程中具有重要的作用。 www.zwyczy.cn 8. DNA methylation is one of the modification ways which exist in all kinds of organisms widely. 这一修饰现象广泛存在于多种生物体中，且与肿瘤的进展密切相关。 www.fabiao.net 9. "DNA methylation in the kidney is different from DNA methylation in the liver, " he says. “肾脏中的DNA甲基化和肝脏中的DNA甲基化是不同的”。 www.bing.com 10. DNA methylation is a common event in malignances and implicated in tumor initiation and progression. DNA甲基化是恶性肿瘤普遍存在的分子生物学改变，与肿瘤的发生和发展密切相关。 www.chemyq.com 1. Here is to summarize the research progress of DNA methylation in colorectal cancer. 现就结直肠癌中的DNA甲基化研究进展作简要综述。 www.bing.com 2. Alterations in DNA methylation, an important regulator of gene transcription, lead to cancer. 对调节基因转录起重要作用的DNA甲基化的异常将导致癌症的发生。 www.med66.com 3. DNA methylation plays a key role in transgene silencing. DNA甲基化是引起外源基因沉默的主要原因。 www.ceps.com.tw 4. This constantly growing data base has become a key resource in the field of DNA methylation research. 不断增长的数据，已成为DNA甲基化研究领域的重要资源。 www.biositemap.com 5. Epigenetic alterations, such as abnormal DNA-methylation patterns, are associated with many human tumour types. 表观遗传改变，如异常的DNA甲基化模式，都与许多人类肿瘤的类型。 www.syyxw.com 6. DNA methylation, amongst the known epigenetic modi? cations, appears to play a crucial role in leukaemogenesis. 在已知的表观遗传修饰中，DNA甲基化似乎在白血病形成中起到一个重要的作用。 www.chinapubmed.net 7. Epigenetic processes, such as DNA methylation, are known to regulate tissue specific gene expression. 已知表观遗传过程，例如DNA甲基化调控组织特异基因表达。 www.chinapubmed.net 8. DNA methylation is a kind of normal endogenous modified mode, which is fulfilled by DNA methylation transferase. DNA甲基化是真核生物DNA的正常内源性修饰方式，它由DNA甲基化转移酶催化发生。 www.chemyq.com 9. DNA methylation is attracting more and more attention in the research of tumor and its diagnosis and cure. DNA甲基化在肿瘤发生发展机制的研究及肿瘤的诊断与治疗中越来越受到重视。 goabroad.zhishi.sohu.com 10. We further show that CTCF binding to CD45 exon 5 is inhibited by DNA methylation, leading to reciprocal effects on exon 5 inclusion. 进一步的研究表明CD45的外显子5与CTCF的结合受到DNA甲基化抑制，从而导致第5外显子包含的相互影响。 www.xinkexue.com 1. DNA methylation was also measured at days 15 and 29 after the first treatment cycle. 在首个治疗周期后的第15天和29天还测定了DNA甲基化。 chinapubmed.net 2. DNA sequencing, which is rapidly dropping in price, can also be used to study DNA methylation. DNA测序也可被用于研究DNA甲基化，且成本已大大降低。 www.bing.com 3. Homocysteine-mediated Aberrant DNA Methylation in Vascular Smooth Muscle Cells and Its Potential Pathogenic Mechanism 高半胱氨酸在平滑肌细胞中介导DNA甲基化及机制的研究 www.pibb.ac.cn 4. Radiation-induced DNA methylation profile changes and its impact on mechanisms of radiation carcinogenesis 电离辐射诱导的DNA甲基化模式改变及其在辐射致癌机制研究中的意义 www.ilib.cn 5. Analysis of Genomic DNA Methylation Level in Radish under Cadmium Stress by Methylation-sensitive Amplified Polymorphism Technique 镉胁迫下萝卜基因组DNA甲基化敏感扩增多态性分析 www.ilib.cn 6. Many studies have explored the mosaic patterns of DNA methylation and histone modification in cancer cells on a gene-by-gene basis; 很多研究已经在逐基因地基础上探寻了癌症细胞中DNA甲基化和组蛋白质修饰的镶嵌模式； www.chinapubmed.net 7. Relationship between Individual DNA Methylation Percentage Difference and Carcass Traits in Pig 猪个体DNA甲基化百分差异与胴体性状的关系 www.ilib.cn 8. The relationship between tumorigenesis and its cure and DNA methylation 肿瘤的发生及治疗与DNA甲基化的关系 zhidao.baidu.com 9. Effect of spleen tyrosine kinase expression re-activation by inhibition of DNA methylation on oncogenesis growth of gastric cancer 脾酪氨酸激酶基因的再激活对胃癌生成和发展的影响 www.ilib.cn 10. Determination of DNA Methylation Contents Both in the Blood and Muscle Tissue of Pigs and Significant Difference Analysis 猪血液和肌肉组织DNA甲基化含量的测定 www.ilib.cn 1. The antioxidative vitamins reduce atherosclerosis and protect DNA methylation of high-fat diet rabbits 抗氧化维生素减轻高脂饮食兔动脉粥样硬化及保护DNA甲基化的作用 www.ilib.cn 2. Relationship between DNA methylation and esophageal carcinoma DNA甲基化与食管癌的关系 www.ilib.cn 3. Regulation of DNA methylation on the expression of tumor suppressor gene and oncogene in human colon cancer cell lines 癌相关基因在结肠癌中的表达及其甲基化调控 service.ilib.cn 4. Stress Treatments and DNA Methylation Affected the Somatic Embryogenesis of Citrus Callus 逆境处理和DNA甲基化影响柑橘体细胞胚发生 www.ilib.cn 5. Role of DNA methylation in control of tumor suppressor gene and oncogene expression in colorectal carcinoma DNA甲基化对大肠癌相关基因表达的调控意义 www.ilib.cn 6. The Method to Determine the Global Levels of DNA Methylation in Paulownia Leaves 泡桐叶片总DNA甲基化水平测定方法 www.ilib.cn 7. DNA Methylation, Histone Modifications and Genes Silencing DNA甲基化、组蛋白修饰与基因沉默 ilib.cn 8. Biological Implications of DNA Methylation and DNA Methylation Assays DNA甲基化的生物学意义及其检测方法 168.160.184.82:8080 9. Relationship between DNA methylation aberration and human tumor DNA甲基化异常与人类肿瘤 www.ilib.cn 10. The relationship between DNA methylation and tumour generation and therapy DNA甲基化与肿瘤发生及治疗 www.ilib.cn 1. The Progress about DNA Methylation and its Role In Cervical Cancer DNA甲基化及其在宫颈癌中的研究进展 www.ilib.cn 2. DNA Methylation in Plants and Its Epigenetic Function 植物DNA甲基化及其表观遗传作用 www.ilib.cn 3. Progress in the Studies of DNA Methylation and Transgenes Silencing in Transgenic Plants DNA甲基化与植物转基因沉默研究进展 service.ilib.cn 4. Changes of DNA methylation during differentiation of human glioma cells induced by NDGA NDGA诱导人胶质瘤细胞株分化过程中基因组甲基化及甲基转移酶的变化及意义 www.ilib.cn 5. Effect of aberrant DNA methylation on the expression of cancer-related genes in Cd-transformed cells 镉转化细胞DNA异常甲基化对肿瘤相关基因表达的影响 www.ilib.cn 6. Applications of DNA Methylation Markers in Forensic Medicine DNA甲基化标记法医学应用探讨 www.ilib.cn 7. The Relationship of DNA Methylation and Histone Methylation DNA甲基化与组蛋白甲基化的关系 www.ilib.cn 8. Aberrant DNA Methylation and Histone Modification in Tumor 肿瘤DNA异常甲基化与组蛋白修饰 www.wanfangdata.com.cn 9. Aberrant DNA Methylation and Tumor Invasion and Metastasis DNA异常甲基化与恶性肿瘤的侵袭和转移 service.ilib.cn 10. Relationship between status of DNA methylation and folic acid in gastric precancerosis lesions 胃癌前病变中DNA甲基化状态与叶酸 www.ilib.cn 1. Review and evaluation of methodology of research on DNA methylation DNA甲基化研究方法的回顾与评价 168.160.184.78 2. Prospects of DNA Methylation and Molecular Diagnosis of Tumors DNA甲基化及其在肿瘤分子诊断中的前景 www.ilib.cn 3. Effects of DNA Methylation Difference Growth Traits DNA甲基化差异对猪生长性状的影响 www.ilib.cn 4. Study on the mechanisms of DNA methylation abnormality in cancer 肿瘤基因组甲基化异常机制研究进展 www.ilib.cn 5. Genetic and epigenetic effects of DNA methylation in cancer DNA甲基化在肿瘤发生中的作用 www.journals.zju.edu.cn 6. Cloning of leukemia associated gene WIT-1 and aberrant DNA methylation in acute myeloid leukemia 急性白血病相关基因WIT-1的克隆及临床意义 www.ilib.cn 7. Study on Aberrant DNA Methylation of Genomic DNA in Lung Cancer Tissue 肺癌组织基因组DNA异常甲基化的检测与分析 www.ilib.cn 8. The study of genome DNA methylation in systemic lupus erythematosus 系统性红斑狼疮患者基因组DNA甲基化水平的初步研究 168.160.184.82:8080 9. Advance in DNA methylation profiles of gastric cancer 胃癌DNA甲基化谱研究进展 www.ilib.cn 10. Effect of cholesterol on genomic DNA methylation level of human vascular endothelial cells 胆固醇对血管内皮细胞基因组DNA甲基化的影响 www.ilib.cn 1. The Study of DNA Methylation and Demethylation on Marek's Disease Virus Genome 马立克氏病毒DNA转录区和非转录区甲基化及脱甲基化的探讨 www.ilib.cn 2. Study on progress of DNA methylation inhibitors 脱氧核糖核酸甲基化抑制剂的研究进展 www.ilib.cn 3. Clinical application of marker based on DNA methylation in gastrointestinal tumor DNA甲基化标志在胃肠肿瘤中的临床应用 www.ilib.cn 4. DNA Methylation and its Effect on Cancer 甲基化及其对肿瘤的作用 www.ilib.cn 5. Effects of Heavy Metal on the DNA Methylation Level in Rice and Wheat 重金属对水稻和小麦DNA甲基化水平的影响 www.ilib.cn 6. The study of genome DNA methylation in rheumatoid arthritis 类风湿关节炎患者基因组DNA甲基化水平的初步研究 168.160.184.78 7. Effect of DNA methylation and histone decoration on tumor DNA甲基化和组蛋白修饰在肿瘤中的作用 www.ilib.cn 8. Influence of cadmium and lead on the DNA methylation level of loach Misgurnus anguillicaudatus 镉铅对泥鳅DNA甲基化水平的影响 service.ilib.cn 9. The Roles of DNA Methylation in Human Neoplasms 肿瘤相关基因过甲基化的研究进展 www.ilib.cn 10. Effect of DNA Methylation on Cell Senescence DNA甲基化在细胞衰老中的作用 www.ilib.cn 1. Advance in DNA methylation related to gastric cancer 与胃癌相关的DNA甲基化研究进展 www.ilib.cn 2. The Effect of Aberrant DNA Methylation in Human Tumors DNA异常甲基化在肿瘤中的作用 service.ilib.cn 3. ZHANG Lin, LIU Hui. Nonparametric Bayesian Clustering Methods of DNA Methylation Microarray. Acta Automatica Sinica, 2012, 38(10): 张林，刘辉.DNA甲基化微阵列的非参数贝叶斯聚类算法.自动化学报，2012,38（10）： blog.sina.com.cn |
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