autophagy

We also list the caveats that must be considered when deciding whether or not autophagy is an important effector mechanism of cell death.

In many cases, it is agreed that this autophagic cell death is cell death with autophagy rather than cell death by autophagy.

The actual role of autophagy in antitumor effects of these drugs, however, depends on concentrations of drugs and the types of tumor cells.

Conceivably, autophagy contributes to cellular senescence establishment and is an effector mechanism of cellular senescence.

In control group, amoeba was full of fragment of E. coli. There was merely little autophagy with fewer autophagic structures in amoeba.

Autophagy stabilizes intracellular environment and maintains cell survival through balancing anabolic metabolism and catabolism .

Autophagy is an important process in which preformed lysosomes process endogenous substrates in cells.

Autophagy is an evolutionarily conserved and lysosome dependent protein degradation pathway, which exists in almost all cell types.

Thus, we have demonstrated proof of principle for a new approach for discovery of small-molecule modulators of mammalian autophagy.

As part of this work, several recent studies have focused on autophagy in heart disease elicited by changes in hemodynamic load.

Defective autophagy plays a significant role in human pathologies, including cancer, neurodegeneration, and infectious diseases.

Autophagy, or "self-eating, " is an essential component of cellular survival and defense against invading organisms.

The ultrastructural and biochemical results clearly show that the autophagy pathway is significantly activated in neurons after TBI.

Autophagy regulates the intracellular homeostatic mechanism that mediates the degradation of proteins and organelles.

Here, we review recent studies of cardiomyocyte autophagy in load-induced disease and address molecular mechanisms and unanswered questions.

These results provide solid ultrastructural evidence showing that the autophagy pathway is activated after TBI.

Autophagy is an adaptive response of cells to physiological and pathological conditions.

Future studies will determine whether and how manipulation of the autophagy pathway improves post-TBI recovery.

Therefore, regulating the activities of autophagy may be a new target of cancer therapy.

This review focuses on the characteristics of autophagy and its relationship with cancer.

Therefore, activation of the autophagy pathway may play a key role in removing damaged cellular components after TBI.

ABSTRACT: Objective To evaluate the characteristics of autophagy in fibrotic and postoperative remnant liver.

The autophagy pathway is the chief route for bulk degradation of damaged cell membranes, neuronal processes, and organelles after TBI.

Autophagy is a biology process that recycle the macromolecular substances and maintain cell stability by self digestion.

Autophagy generally exists in eukaryotic cells. It happens in normal cells through physical or pathological process in cell cycles.

The ability to activate autophagy within these cells could prove invaluable in the treatment of neurodegenerative disorders.

Deretic is fascinated with autophagy both as a fundamental biological process and as an effector of innate and adaptive immunity.

Furthermore, genetic evidence of autophagy as an anti-age effector has been provided in lower eukaryotes.

Autophagy is the chief machinery for bulk degradation of superfluous or aberrant cytoplasmic components.

According to Li, autophagy is the only known process that gets rid of abnormal proteins within cells.

Autophagy, appears to involve an active participation of the vacuolar membranes.

The further work is to explore the mechanism of cross-talk between the high level of autophagy and apoptosis.

This review focuses on the processes of autophagy and its roles in cell survival and cell death.

Eukaryotic cells use autophagy and the ubiquitin-proteasome system as their major protein degradation pathways.

The role of autophagy-lysosome pathway in neurodegeneration associated with Parkinson's disease.

But it was thought that the brain was largely resistant to autophagy under these conditions.

Recent evidences suggest autophagy is a double-edged sword in Tumorigenesis and Metastasis.

Results In the control group, amoeba was full of fragment of E. coli, the level of autophagy was low.

This article summarizes the role of autophagy in Tumorigenesis, Metastasis and Therapy.

Remarkably, autophagy may also play a role in determining the human life span.

When the autophagy was blocked by the researchers, though, those hunger signals were blocked.

Here, we evaluate the accumulating body of literature that argues that cell death occurs by autophagy.

Besides, it is closely related to the autophagy, mitochondrial apoptotic pathways, and changes of endogenous and exogenous factors.

Fullerene C60 has been shown to induce certain static features of autophagy, but no detailed studies have been undertaken.

Cytoplasmic components may well be scavenged by selective autophagy.

The presence of autophagy inhibitor greatly improved cell survival under ER stress.

Mice without the genes needed for autophagy quickly develop Parkinson's-like symptoms.

Write the word addiction, love addiction, such as drug use autophagy induced by.

Large numbers of studies have shown that autophagy promotes cell's survival in starvation.

This article mainly reviews the function of autophagy in pathogens.

Autophagy plays an important role in cleaning dust particles and the injured mitochondria.

In the current study, they report on a mutant strain of P. gingivalis (PG0717) that does not induce autophagy.

Autophagy is a vacuolar process of cytoplasmic degradation by lysosome.

Autophagy is a lysosomal degradation pathway that is essential for survival, differentiation, development, and homeostasis.

abstract: Autophagy plays an important role in the innate and adaptive immune.

The effect of autophagy on the chemotherapy was evaluated by cell viability assay and colony-forming test.

ARHI, one of the autophagy related gene, may play a part in the occurrence and progress of tumor through regulating autophagic capacity.

Acridine orange and MDC staining were conducted to detect the autophagy of U87-MG cells.

Autophagy reduces inflammation but at the same time permits the clearance of microbial infection.

Paradoxically, although autophagy is primarily a protective process for the cell, it can also play a role in cell death.

Autophagy and apoptosis may be triggered by common upstream signals, and sometimes this results in combined autophagy and apoptosis;

Inhibition of autophagy influences the autophagic apoptosis induced by vincristine

Molecular mechanism of autophagy associated with diseases

Autophagy and Its Roles Played on Cell Metabolism and Diseases

Autophagy and its role in carcinogenesis

The role of autophagy in pharmacological actions of anticancer drugs

Autophagy in Immunity and Infection: A Novel Immune Effector

Inducement of Tumor Cell Autophagy and Cell Cycle Analysis

The role of autophagy in cell survival and tumor development

Autophagy in Fungi and Mammals