vaccine

WHO will now work to ensure that this vaccine gets to groups who otherwise would have no access to pandemic vaccines.

Analysis of those studies was completed: all of them showed reduced mortality in the children vaccinated with all of the vaccines.

VLP do not contain viral nucleic acid, which means that VLP has no pathogenicity and suggested as a promising platform for vaccines.

Indeed, the universal vaccines developed so far do not totally prevent infection, as the strain-specific vaccines can do.

a sore arm; maybe a bit of a temperature overnight; and then settling down. Serious side effects of these vaccines are very uncommon.

I mean, hygiene, vaccines, antibiotics -- you know, the same sort of time frame.

What is still unclear was how long the protection lasts and how much each of the two vaccines contributed.

The key decision in pursuing vaccines was, would we be ready to accept that this division will be losing money?

"If we knew what the key immune responses were to effective vaccines it would be easier to evaluate them, " he said.

The proteins used in vaccines are usually found on the surface of the disease-causing agents and can be generated in the laboratory.

Needle-free liquid jet injectors have been used for more than 50 years for parenteral delivery of vaccines and drugs.

For animals, vaccines are usually effective to stave off the virus, while humans can start prophylaxis within a week of exposure.

And hypodermic needles do not even deliver vaccines to the best place in the body.

He said the safety and efficacy of all swine-flu vaccines will be closely monitored by regulators, doctors and scientists around the world.

Making new influenza vaccines ready to immunize people generally takes five to six months after first identification of the pandemic virus.

"The data indicate a similar safety profile to that of seasonal vaccines, " said Professor David Salisbury, SAGE Chair.

If any of these vaccines do prove effective, they will be relatively easy to manufacture.

He said the agency also has brought in tetanus vaccines, which are potentially life saving for wounded patients.

The public health community has gotten markedly better at distributing effective vaccines to the children who need them.

They said tests in mice showed that their new vaccines are safer than live-virus vaccines and appear to work just as well.

So producing pandemic vaccines as a precaution may turn out to be a waste of resources with deadly results.

Vaccines used to be seen as low-technology, commodity products that fetched low margins in rich countries and none at all in poor ones.

Influenza vaccines have been used for more than 60 years and have an established record of safety in all age groups.

If there's no valid scientific evidence to support a link between vaccines and autism, why is there so much talk about such a link?

used for quality control of the conjugate vaccines and vaccine intermediates must be validated.

Extrapolation from a few examples that an alternative preservative can be used for all vaccines is speculation.

There was no safety testing of Thimerosal in children before it was put into pediatric vaccines.

In recently developed vaccination strategies, DNA vaccines display advantages over other vaccines and have been a research hot spot.

They did not expect genes, viruses, or vaccines to transform their subjective suffering into an objective determination. They took over.

Contrary to what some people believe, poor parenting practices and vaccines do not cause autism spectrum disorders.

Can it be determined that there is a relationship between the vaccines and the illnesses that afflicted the children?

HIV vaccines use inactive viruses to introduce parts of HIV into the body to cause an immune response that should prevent future infection.

She said many producers traditionally use drug treatments and live parasite vaccines against coccidiosis .

Such high levels of corruption could also have very serious consequences, for instance, when food and vaccines did not reach poor people.

Personal hygienic habits were considered most effective. Overall, people did not rely on vaccines excessively.

Dr. Haupt of Merck said the vaccines' price was worth it for the deaths prevented and the tests avoided.

Such a treatment would have to come from the makers of vaccines for the more ordinary, seasonal strains of flu.

Sanofi and other drugmakers annually produce about 300 million doses of seasonal flu vaccines, the kind used for annual flu shots.

Gates said he is optimistic that with the available vaccines, financial resources, and new country commitments, polio could soon be history.

All the pandemic vaccines have had their own safety tests, and almost all are based on seasonal flu vaccines used for years.

Such chemicals, known as adjuvants, are commonly used in vaccines to reduce the amount of antigen needed to trigger an immune reaction.

During the war, Sabin's vaccines protected thousands of U. S. troops against such diseases as dengue fever and Japanese encephalitis.

There are many vaccines have temporal association with GBS. But causal association between them is not concluded.

Vaccines replicate this process by introducing a whole pathogen or fragments of it that will be recognized as a foreign invader.

So far, evidence suggests that current seasonal influenza vaccines will not be protective against pandemic influenza.

Vaccines used for prophylactic vaccination shall conform to the quality standards of the State.

WHO will now work to see that these vaccines are distributed to those who need them.

Conclusion Safety of different hepatitis A vaccines is all good.

The British doctor who originally published the finding about vaccines and autism has since been found to have falsified his data.

GSK said on Tuesday the project's first vaccines would be available "over the next few years" .

Similarly, whole inactivated virus vaccines did not show efficacy and their development has been stopped.

You could see an avian strain that would infect the poultry flocks, and then we would have no eggs for our vaccines.

Fortunately, those scourges are virtually unknown to modern generations that have had access to vaccines all their lives.

The antigens may be used in pneumococcal vaccines, but may also be used as components in vaccines for immunizing against multiple pathogens.

He said U. S. scientists need more time to finish research into how well new vaccines and drugs work against the virus.

In September, a $105 million trial of a novel combination of two older vaccines was the first to show protection against HIV infection.

For group B, polysaccharide vaccines cannot be developed, due to antigenic mimicry with polysaccharide in human neurologic tissues.

Certainly, vaccines have long been a mainstay in the arsenal against infectious diseases.

The firm will then be able to use it, and the method used to construct it, in its programmes to make fuels and vaccines.

The GAVI Alliance says almost two million children a year die from diseases that vaccines can prevent.

The country is concerned poor countries will not be able to afford or be given access to vaccines derived from the samples.

Rebuilding public sector capacity to develop and test needed vaccines may be an important element of a public health strategy.

As vaccines available initially will not be sufficient, a step-wise approach to vaccinate particular groups may be considered.

At the moment, antibody medicines and vaccines are produced in cell cultures inside stainless steel fermenters.

Gearing up to manufacture vaccines that meet international standards is a costly and complex process.

They produced a pair of synthetic vaccines, each containing genes from two of the four virus types.

Vaccines began to provide protection against tuberculosis, flu, measles, mumps and other diseases that once killed many children.

Physicians must be cognizant of the cyclical changes in bacteria as well as new vaccines and antibiotics best suited to address AOM.

"But it is expected that it will be a further one to two years before vaccines manufactured in China will be prequalified, " he said.

So far, evidence suggests that it is unlikely that seasonal influenza vaccines will be protective against the new pandemic virus.

"The joint venture with Neptunus, which focuses on flu vaccines will hopefully in the future create greater domestic capability, " he said.

The committee discussed a number of general issues relevant to all vaccines as well as a number of vaccine-specific issues.

Vaccines are powerful weapons in the human arsenal against infectious disease and among the most effective interventions in public health.

AFTER vaccines and bed nets, could the humble cooking stove be the next big idea to save millions of lives in poor countries?

The roll out of such vaccines could help build synergies among immunization, cancer control and sexual and reproductive health.

They have been used for many years in some vaccines.

So silk experts at Tufts University have come up with a potential solution: encase the vaccines in silk protein.

Ways were sought to shorten the time between the emergence of a pandemic virus and the availability of safe and effective vaccines.

There is an increasing need for novel vaccines able to stimulate efficient and long-lasting responses which have also low production costs.

We normally sell our vaccines directly to doctors so one of my jobs is to discuss our new products with doctors.

No vaccines would be available until at least March.

However, to have the greatest impact, pandemic vaccines need to be available quickly and in large quantities.

Whatever happens, they and their families will have access to antiviral drugs and, within a few months, to vaccines.

The vaccines are approved for use in pregnant women and children over the age of six months.

The findings from these studies do not challenge the safety of existing thiomersal-containing vaccines in infants.

Some of these programs have made great progress against polio and other diseases preventable by vaccines.

The polio eradication plan is seen as part of an overall effort to provide vaccines to children around the world.

In many countries, for inactivated vaccines supplied in multi-dose vials, the presence of a preservative is a regulatory requirement.

"Most of the old vaccines are undervalued, " he said.

Most vaccines take three years to get that sort of endorsement, Dr. Harper said, and then 5 to 10 more for universal acceptance.

FOR decades vaccines were a neglected corner of the drugs business, with old technology, little investment and abysmal profit margins.

If vaccines are to be provided from overseas supplies, special considerations must be taken.

But classical vaccines do not always work in all people, nor can they guard against all illnesses.

This week, domestic media reported on bogus rabies vaccines and dumplings found to have been stuffed with cardboard scraps.

Most vaccines work in terms of stimulating something known as antibody, which is a protein substance in the body.

Personalized vaccines could also be produced with genetically engineered bacteria, but bacteria-grown vaccines aren't ideal, either.

After the 1960s, China began to inoculate BCG, pertussis, diphtheria, tetanus, measles and poliomyelitis vaccines.

While the company struggled to fulfil its early promise , the acquisition of a vaccines business in 2000 would make his fortune .

It noted that the possibility of an age-dependent risk of intussusception should be taken into account in assessing rotavirus vaccines.

Vaccines are based on an antigen - the ingredient that actually stimulates the body's immune response - plus other components.

Some seasonal influenza vaccines that are intended for people known to have poor immune responses to immunization contain an adjuvant.

A: Many countries, including the USA, have not licensed vaccines with adjuvants of any kind yet.

Thiomersal has been used since the 1930s in the manufacture of some vaccines and other medicinal products.

Several adjuvants are already contained in licensed vaccines, and others are likely to be available in coming years.

One of those conditions is a severe allergy to eggs, because in years past all flu vaccines were based in egg serum.

However, the WHO says that vaccines are not the only weapon in the fight against swine flu.

The next generation of HIV vaccines are known as "mosaics. "

If human beings developed a stimulating antibody production of both vaccines, it will be able to effectively fight HIV.

However, squalene was not added to the vaccines administered to these veterans, nor was it used in the manufacturing process.

CONCLUSIONS Safety of NIP vaccines and the quality of immunization services were satisfied, but it still needs to be strengthened.

Delivering vaccines to the developing world poses just such a challenge.

The existing vaccines can only reduce the amount of virus, rather than totally inactivating it.

Vaccines are one of the greatest achievements in medicine and public health.

Mass vaccination against swine flu could begin within weeks, following the approval of two vaccines by the European regulator today.

The adjuvant used in most vaccines today does not provoke a full adaptive response; instead it favors B cells over T cells.

Treatments called therapeutic cancer vaccines are ways to modify cells to help the immune system recognize the risk.

The gene could be a target for a range of human therapies, including vaccines and anti-virals, to treat obesity, said Pasarica.

To help prevent diarrhea, the report suggests that children receive both the rotavirus and measles vaccines.

Recently, the pneumococcal vaccines in the global scope of large-scale immunization have caused germs epidemiology to be changed.

Biotechnology, they say, can also be used to provide a kaleidoscope of other products ranging from cleaner plastics to consumable vaccines.

Then, when a problem arises, an answer can be found quickly. If pathogens can be designed by laptop, vaccines can be, too.

To determine the validity of the shake test for detecting freeze damage in aluminium-based, adsorbed, freeze-sensitive vaccines.

It is still unclear how effective the vaccines currently being developed would be if H5N1 changed and sparked a human flu pandemic.

Crumpacker said the study suggests vaccines and antiviral drugs may offer a new approach at treating hypertension.

You may have read or seen various of the "antivax" crowd saying that the H1N1 vaccine is as evil as they think most other vaccines are.

Cell-based manufacturing is already used to make vaccines against many other diseases, so it might win rapid approval for flu.

Safe and effective vaccines have been available and used for more than 60 years.

The vaccines are supposed to wear off in a year.

Public misperceptions worry me, like the belief that vaccines are dangerous.

Delegates directed WHO to help countries reach higher immunization coverage and to encourage development of new vaccines.

Delegates directed WHO to help countries reach higher immunization coverage and to encourage development of new vaccines.

To exempt children from other vaccines, parents must provide a medical reason; for Gardasil, they do not.

It has also teamed up with Synthetic Genomics Vaccines, a young American firm, to develop a variety of "seed" viruses.

Nanoemulsion platforms are already capable of developing vaccines from very diverse materials.

This chapter is, to a certain extent, based on the German standards and the vaccines marketed in Germany.

These studies give further support to the safety in infants of thiomersal-containing vaccines in the amounts used in existing vaccines.

This is something that we have been after for a long time but the next stage is crucial. Many new vaccines fall at the human trial stage.

Safety monitoring systems are an integral part of strategies for the implementation of the new pandemic influenza vaccines.

Are there alternative preservatives that could be used for vaccines ?

The vaccine works differently from conventional vaccines in that it does not prevent infection directly.

Europe could hoard flu vaccines, leaving the U. S. , which has only one manufacturing plant, high and dry.

Although this is one of the fastest vaccines available, Grubman and his colleagues wanted faster protection.

Both vaccines also appeared to prevent abnormal, precancerous cell growths found in the cervix, he says.

Better influenza vaccines, weak children, the elderly and patients can be vaccinated in advance to the prevention of influenza.

While vaccines are important, Red Cross officials say they are not the only way for people to stay safe.

Clinical trials on prepandemic vaccines containing adjuvant suggested that two injections were necessary to induce protective immunity.

It lends support to the idea that therapeutic vaccines, which are designed to be taken after someone is infected, might work against AIDS.

These findings do not suggest an association between measles vaccines and SSPE.

Nevertheless, vaccines continue to be developed and tested for safety and immunogenicity .

He said some polio vaccines were made from a live virus.

What would be the public health impact of restricting manufacture, distribution or use of thiomersal-containing vaccines ?

So a simple idea, which we hope is going to change the way vaccines are distributed, in Africa and around the world .

Regulatory authorities have licensed (approved) pandemic vaccines in a number of countries.

The research community has created pipelines of new diagnostics, medicines, and potential vaccines, moving forward after decades of neglect.

Significant efforts have been made by regulatory authorities and manufacturers to further improve and ensure the safety of vaccines.

Other vaccines are currently available, but they do not offer full protection.

Clinical studies of squalene-containing vaccines have been performed in infants and neonates without evidence of safety concerns.

Newly developed cancer vaccines have been continuously applied to clinical trials, and inspirable results have been attained.

Meanwhile, the vaccines' proponents are moving to the next frontier: older women and boys.

Current vaccines to protect against cholera must be kept in cold storage. The need for refrigeration limits use in poor countries.

The introduction of such vaccines could help to develop synergies between vaccination, cancer control and sexual and reproductive health.

Oral cholera vaccines are considered an additional means to control cholera, but should not replace conventional control measures.

The early-stage study only focused on the safety and immune-stimulating ability of the plant-produced vaccines.

Two human trials of candidate vaccines are currently underway in Tailand and the United States and more research is going on.

The trouble with using hens' eggs for making killed or attenuated vaccines is that production cannot be ramped up quickly in an emergency.

Manufacturing practices of aluminium-containing vaccines make a local pharmaceutical cause unlikely.

The scientists gave mice a primary vaccination and two booster vaccines to mimic as closely as possible the schedule used in patients.

No study found any danger to mothers or their babies from having the inactivated flu vaccines that are currently used in the UK.

Vaccines contain dead OR harmless germs. They cause the body to develop substances called antibodies that act to prevent disease.

To prove the principle, he chose cholera, but it should work with other vaccines as well.

Vaccines consisting of a single protein, however, can be grown using widely available equipment, which is much faster and cheaper.

In the USA, vaccines for seasonal influenza are licensed without clinical trials on the basis of a "strain change" .

He says at least 2 experimental vaccines have movedbeyongbeyond laboratory tests and now are now being tested in people.

depleted arsenals of diagnostics, medicines and vaccines as well as insufficient research and development on new products.

Using vaccines for children is an economical and effective way for preventing epidemic diseases and reducing children's death rate.

So vaccines that heavily influence T cell biology are likely to generate T cell reactivity and vaccines that don't are unlikely to do that.

To refocus the immune attack, the idea is to create vaccines containing only the conserved proteins, rather than whole viruses.

At the moment it takes months to produce new vaccines, which is too slow to respond to fast-mutating viruses.

Licensed vaccines, including influenza vaccines, are held to a very high standard of safety.

And people tend to be suspicious about vaccines, especially those recommended for kids and pregnant women.

Injectable vaccines can be useful if the inactive virus is bound up with nanoparticles to increase the immune response.

Although pneumococcal vaccines have helped, serotype shifts and bacterial resistance could work against current treatment practices.

The study confirmed that patients with MMF are more likely to have received vaccines containing aluminium hydroxide adjuvants.

The vaccines will be distributed nationally after the initial lots become available, which is expected within the next four weeks.

The remainder, expected later this year, has been earmarked for HIV and TB treatment and for the provision of vaccines and microbicides.

Members are acknowledged experts from around the world in fields relating to vaccines and immunization.

The response to new outbreaks would be swifter and stronger; the administration of vaccines, broader.

This troubled public-health experts because vaccines are a highly effective way of dealing with diseases.

Work to date on therapeutic vaccines has focused on another immune system mechanism known as T-cells.

Seasonal flu vaccines use either an inactivated or weakened form of the flu virus.

Researchers continue to look for vaccines based on both antibodies and cell-mediated parts of the immune system.

The tip of the spike mutates continually, which means that flu vaccines must be redefined every year.

Inactivated vaccines contain killed viruses or parts of viruses, which cannot cause disease.

Those vaccines will include protection against two of the major killers: respiratory infections and diarrhoeal diseases.

The purpose of this course is to teach the production techniques of various veterinary vaccines.

Clinical studies on squalene-containing vaccines have been done in infants and neonates without evidence of safety concerns.

When a dangerous new virus strikes, the public health system reacts with vaccines or therapeutic drugs.

Potential side effects of this H1N1 vaccine are expected to be similar to those of the seasonal and H1N1 flu vaccines.

Cell cultures of animal viruses have been widely utilized for isolation, research and vaccines production nowadays.

Some of the greatest strides forward for health have followed the development and introduction of new medicines and vaccines.

Expanding the availability of these vaccines creates a level playing field.

So far, the world has not yet developed AIDS can be cured completely effective in preventing drug and HIV vaccines.

By preventing HP infection, the vaccines remove the principal cause of cervical cancer and genital warts, as well as pre-cancerous lesions.

What technologies are being used to grow pandemic influenza viruses to make vaccines?

Improving services to deliver traditional vaccines will reduce the number of vaccine-preventable deaths.

Promising new technologies should be speedily funded to develop reliable methods for mass-producing vaccines in large vats instead.

Vaccines - credited with eradicating diseases such as diphtheria, polio and measles in the United States - sometimes still get a bad rap.

Vaccines, unlike antibiotics, tend to be recommended or mandated by governments.

The third revolution was the introduction of vaccines and antibiotics: many infectious diseases could finally be prevented or cured .

Q: What would be the health impact of restricting thiomersal-containing vaccines ?

That includes stockpiling of face masks and drugs, as well as some additional supplies and production contracts for vaccines.

Elimination of TB is a distant, perhaps an impossible, goal if we do not bring new diagnostics, drugs and vaccines to market.

There are currently no licensed vaccines against malaria or any other human parasite.

Members are appointed by the Director of the WHO Department of Immunization, Vaccines and Biologicals (IVB).

A lack of vaccines for seasonal flu guarantees that many unprotected people will die of the otherwise mundane version of influenza.

American researchers have been testing the best ways to store vaccines in refrigerators.

European regulators have been more enthusiastic than American ones about allowing adjuvants in flu vaccines.

Hello Dr Peters. Just fine thank you. Ricky and I are here for his vaccines.

Current approved vaccines against the H5N1 avian influenza virus require two doses to be fully effective.

In the "combined vaccine" , this play what role the two vaccines, remains to be further studied.

The machine is in operation alongside MMDA's existing labeller and is used in the duel processing of diluents and vaccines.

As with vaccines that contain thiomersal, safe limits have been defined for organic mercury compounds in these products.

The Committee will continue to review the safety data of new rotavirus vaccines from clinical trials and post-marketing surveillance.

Nano Silver can be used in different forms (including injectable in researching for new vaccines ).

The invention discloses porous microspheres and the application thereof in preparing the vaccines of the porous microspheres.

He built his foundation on the promise of life-saving vaccines, reflecting his penchant toward finding technological solutions to problems.

Wheezing and vomiting episodes have been described in children receiving live influenza vaccines.

No efficacy data are available using a neonatal schedule for any of the rotavirus vaccines.

No other clear association has been found with either seasonal or other pandemic influenza vaccines.

WHO advises all countries administering pandemic vaccines to conduct intensive monitoring for safety and report serious adverse events.

Deciding when, or indeed whether, to switch capacity from producing seasonal vaccines will not be easy.

However, despite the successful application in many animal models, the efficacy of DNA vaccines in human clinical trials is unsatisfactory.

Both modified live attenuated virus and inactivated virus vaccines have been developed for veterinary use.

And the latest vaccines incorporate clever new insights into how malignant cells can be tagged, exposed and destroyed.

It says new vaccines against the pneumococcal bacteria and rotavirus could save more than one million children each year.

Strategic partnerships with industry and new approaches to health financing to ensure equitable access to these vaccines are critical.

In the next decade or so, it is likely that the number of available vaccines will double from the current 20.

It provides hard to find information addressing therapeutic drugs made from proteins as well as protein-based vaccines.

However, plant-grown vaccines, which lack side effects, could allow earlier, more aggressive management of the cancer.

All test DNA vaccines were formulated with the company's VaxfectinTM adjuvant.

Conclusion The mean efficacy dilution can be used as the parameter to evaluate the immune dose on inactivated HAV vaccines.

But work is at an early stage, and such vaccines are unlikely to reach the market for several years.

We have drugs and vaccines, particularly in developed countries, which should markedly reduce the burdens of the disease.

Time constraints mean that clinical data at the time when pandemic vaccines are first administered will inevitably be limited.

Researchers are already working on the next generation of vaccines.

Preservatives are a component of some of the vaccines provided to countries in multi-dose vials.

We have more work to do before these safe and highly effective vaccines and antiviral treatments are fully developed and approved for use.

But, like human vaccines, they have to be updated continually as new flu mutants evolve.

Using newly developed vaccines against pneumococcal pneumonia and rotaviral diarrhoea could bring enormous gains.

Using a potent neurotoxin in the vaccines given to infants and children has seriously eroded the public's trust in the vaccine program.