tumor cells

Just a few tumor cells in blood are enough to spread cancer to other parts of the body.

Conclusion HASL can lyse tumor cells to a certain extent , but there was no obvious specificity.

Vaccine strains of measles virus have been used to kill tumor cells in a number of tumor types including one type of adult brain tumor.

Maybe tumor cells are being disguised as skeletal muscle cells, and this is why it seems as if it is so rare.

The expression of genes that inhibit cancer development, so-called tumor suppressor genes, is often lost in tumor cells.

Ertl, M. D. , was used to activate the T cells that recognize a molecule on the surface of the tumor cells.

Some cancer cells are able to synthesize components of basement membrane, which may be responsible for the invasive activity of tumor cells.

It was previously believed that the movement of tumor cells by the lymphatic system was a more passive process.

In the absence of antigen, the T cells did not interact with tumor cells, and could not sustain an active migratory behavior within tumors.

Soon after a toxic drug is found to kill tumor cells, for instance, drug-resistant variant cells grow up in their place.

The actual role of autophagy in antitumor effects of these drugs, however, depends on concentrations of drugs and the types of tumor cells.

"The transporter was failing to take up the drug, so there were a bunch of different drug-resistant tumor cells, " said Govindarajan.

Tumor cells send signals to stimulate the growth of the cells that form the scaffold in which the tumor cells grow, known as fibroblasts.

Some experts believe that drugs that kill most tumor cells do not affect cancer stem cells, which can regenerate the tumor.

The researchers say they have also been able to develop tumor cells in the lab, enabling them to run tests without actual tumors.

Emodin can inhibit the growth of liver tumor cells in vitro and in vivo, inducing cell apoptosis is one of its mechanisms.

Macrophages were able to squirm through the white blood cell blockade and start killing the tumor cells.

Radiation resistance of hypoxic tumor cells is one of the key points in radiation oncology and biology.

"The most aggressive tumor cells have the highest levels of this protein, " he said.

In vitro tumor chemosensitivity assay has been widely used to determine die response of tumor cells to anticancer drugs.

So tumor cells can only escape from the mammary gland by accomplishing a whole series of modifications.

When this molecular glue is broken down, tumor cells start to migrate and spread throughout the body.

But recent reports show that the metastatic phenotype of tumor cells can be reversed to normalcy after injecting to the blastocyst.

Unlike tumor cells, the transplanted stem cells achieved homeostasis, growing to a stable, constant level and ceasing replication.

Tumor cells display progressive changes in metabolism that correlate with malignancy, including development of a lipogenic phenotype.

The CAR was engineered to bind to another protein called CD19 that's present on the surface of normal B lymphocytes and all CLL tumor cells.

Circulating tumor cells (CTC) can be identified and characterized in blood of patients with many solid tumors, particularly breast cancer.

Then, once the tumor cells had been destroyed, we saw a dramatic change in the behavior of the activated T cells.

We can easily introduce changes among the cells or insert a few tumor cells to test the abilities of the nanoparticles to recognize them.

Their findings suggest that testing tumor cells for levels of these proteins could help to predict patient response to antitubulin agents.

Then the functional magnetic nanoparticles were used to detect pancreatic tumor cells.

Light microscope, the tumor cells varied forms, can be divided into fibrous, protoplasmic, obesity, type of glial cell tumors.

The dyeing method is mainly used in recognizing the ripeness of cells and identifying malignant tumor cells and the type of acute leukemia.

There was also evidence that the foreign immune-stimulating gene wasexpressed inside the tumor cells.

The concept of existence of circulating tumor cells(CTCs)has a history of over 100 years.

Aberrant DNA methylation is one of the major characteristics of tumor cells in addition to genetic and other epigenetic alterations.

The capability of NK cells to kill tumor cells mainly depends on the synthesis of stimulatory and inhibitory signals on the cells surface.

CONCLUSIONS: Tissue factor stimulated tumor metastasis through promoting intravascular migration of tumor cells.

The basement membrane (BM) is a specialised form of extracellular matrix (ECM), which is a major barrier to tumor cells during metastasis.

Researchers this year turned a searchlight on the errant DNA that leads tumor cells to grow out of control.

In a test tube, the lymphocytes are perfectly capable of killing tumor cells.

The mechanism of hyperthermia and chemotherapy in the treatment of the tumor cells was explored at both macroscopic and microscopic levels.

The main anticancer mechanisms of Tetrandrine were inducing tumor cells apoptosis, down-regulating the expression of MRP.

Results The nuclei of tumor cells had a high frequency of mitoses. Tumor cells showed diffuse distribution or nest the bands of arrangement.

Multilocular cystic renal cell carcinoma. Tumor cells line delicate fibroascular trabeculae. The tumor cell is of clear cytoplasm.

Giving chemotherapy together with a monoclonal antibody may kill more tumor cells.

Tumor cells can cheat death by making a protective barrier from an enzyme that bonds with a protein.

But by targeting tumor cells while avoiding normal cells, doctors could treat the neuroblastoma aggressively while minimizing side effects.

Microscopically, all tumor cells revealed irregular contours, high cellularity and pleomorphism, located mainly in the dermis.

And adenoviruses that are designed to bind to receptors on the surfaces of tumor cells can still invade a small proportion of healthy cells.

This gene is missing in SCC tumor cells and, as it turns out, provides the signal for cells to stop multiplying.

Results: The increased nuclear DNA content, widespread DNA distribution and aneuploid DNA pattern were found in malignant tumor cells.

Lung metastases were also observed in a VEGF-dependent manner following tail vein injection of tumor cells.

Rare earth has certain potential of antitumor, which inhibits the growth of tumor as well as killing the tumor cells.

Platelets shelter and feed tumor cells that stray into the bloodstream, making it easier for cancer to spread, or metastasize.

and an inhibitor activity of the compound on Staphylococcus aureus and tumor cells.

targeted release drugs at the tumor site in liver cancer treatment, effectively inhibit tumor cells and reduce toxicity.

From this perspective, increasing the nutrient will not speed up the growth of tumor cells.

Objective: The killing effect on tumor cells by combination of low intensity ultrasound and photosensitizer has good prospects for research.

Moreover, transformation of tumor cells is involved in oncogene amplification or promoter enhancement.

Radioactive particle can continuous affect the tumor by releasing ray with relative minor energy, and then kill the tumor cells thoroughly.

This switch involves numerous alterations that allow tumor cells to complete the complex series of events needed for metastasis.

Spider toxins in vitro and vivo were significantly inhibit the growth of tumor cells, inducing tumor cell apoptosis and cell necrosis role.

The identification of SARI also provides a new potential reagent for the selective killing of tumor cells, " said Fisher. "

Although the sulfated xenobiotics bind poorly to the ER, both stimulated the growth of receptor-positive breast tumor cells.

After re-acquiring receptors, these tumor cells are expanded by the mitogenic properties of estrogens.

This study demonstrates the clinical value of circulating tumor cells in predicting progression-free and overall survival rates.

The regulation of telomerase activity was also studied during apoptosis of tumor cells.

Prooxidants would generate free radicals and the formation of hydrogen peroxide, which, the scientists hypothesized, might kill tumor cells.

Oral squamous cells carcinoma cells lines were cultured and passaged, the conditional medium of tumor cells were prepared.

Tumor angiogenesis is the growth of tumor cells and tumor-induced microvascular blood circulation in the building process.

the changes of the tumor cells' appearance were observed and evaluated with optical microscope.

Biopsy of the nodule showed nests of clear tumor cells, suggesting metastatic renal cell carcinoma.

Objective Through assessing between in vitro sensitivity of peripheral blood lymphocyte and tumor cells.

Vitamin E succinate(VES) is an effective inhibitor of tumor cells proliferation.

Tumor cells are typically riddled with genetic mistakes that disrupt key cell pathways, removing the brakes on cell division.

In the first set of experiments, the T cells were varied in two groups of mice while the target tumor cells were uniform.

Many pancreatic tumor cells are resistant to gemcitabine, which makes the disease very difficult to treat, explained Govindarajan.

Pertuzumab can even disrupt certain types of HER2 activation in tumor cells that have become resistant to trastuzumab.

CD155 is broadly distributed on normal cells in many tissues at a relatively low level, while over-expressed on certain human tumor cells.

However, this also makes tumor cells more susceptible to viruses, which replicate inside the infected cell until it bursts.

Symptoms a dog with lymphosarcoma exhibits depends largely upon where the tumor cells are in the pet's body.

Extensive local excision was done for those with active growth of tumor cells revealed by pathological examination.

In fact, such signals have been shown to protect tumor cells from the effects of chemotherapy and radiation therapy.

Molecularly targeted nanocarriers deliver the cytolytic peptide melittin specifically to tumor cells in mice, reducing tumor growth.

Methods Inducing differentiation effect of gambogic acid were evaluated by proliferation, morphology and function of tumor cells.

Previous studies shown that LDM have could inhibit the proliferation and migration of endothelial and tumor cells.

The non-viral vector can independently kill the positive malignant tumor cells of the GRP acceptor.

The viruses homed in on the ovarian tumor cells and killed them, ridding the treated animals of the disease.

The goal of radiosurgery is to deplete tumor cells while preserving normal structures.

When VEGF activity is impaired, tumor cells invade deep into the brain in the perivascular compartment.

Tumor cells produce compounds called volatile organic compounds at higher levels than healthy cells.

The reticular fiber staining indicated that the tumor cells located in the outside of reticular fiber.

Conclusions: NDV can kill tumor cells and can be used to treat tumor.

Potentially, the environment of the liver is suitable to the growth of certain tumor cells.

Fortunately, the tumor cells are more susceptible to the drugs than normal cells.

Tumor samples taken from three people with melanoma showed the nanoparticles found their way inside tumor cells.

The chemotherapy drugs will cause injury to normal tissue cells in varying degrees while it make effects on anti tumor cells.

In most cases, the protein that PTEN produces was undetectable in tumor cells, but clearly present in nearby normal cells.

The tumor cells showed different degrees of apoptosis in the thermochemotherapy and chemotherapy groups under electron microscope.

Immunochemistry demonstrated tumor cells were positive in the luminous tissues.

As a result, the immune system does mount some response to tumor cells, but it is rarely adequate to fight off the cancer.

The tumor cells(RB)had direct contact with Bruch? s membrane, and retinal pigment epithelium was disappeared here.

Tumor cells accumulate errors, become totally anarchic, and flout all the rules.

Background characteristics of malignant tumor cells .

Apoptin is coded by the VP3 gene from chicken anemia virus (CAV), and the protein can induce apoptosis of a large variety of tumor cells.

A lot of myelocyte-like tumor cells filled with acidophilus granules were observed in the liver, kidney and spleen tissues, respectively.

A large of tumor cells are scattered or clustered arrangement in the smear, nuclear were round or oval shape, basophilia and marked atypia.

The minicells can be loaded with chemicals and coated with antibodies that direct them toward tumor cells.

By immunohistochemical stain, the tumor cells were strongly positive for chromogranin, synaptophysin, and CD56.

Its cytotoxic effects and dosage-dependent relationship on growth of tumor cells were examined by MTT assay.

METHODS: Expression of tissue factor in tumor cells (HT1080) was analyzed by flow cytometry and immunofluorescence staining .

The tumor cells that were located among retinal pigment epithelium and Bruch? s membrane had necrosis (Nc).

A protocol for frozen storage of the vaccine (transduced tumor cells) is provided.

In the assay presented here, tumor cells are placed in the upper chamber of Boyden migration chamber.

When colon cancer tumor cells are exposed to high pressure they exhibit an increased ability to stick to other cells.

Sometimes during surgery to remove a tumor, cells become detached from the bulk of the tumor.

In the ordinary way normal cell cycle occurs abnormal (as polyploidy) will start the apoptosis in the tumor cells.

Finally, it's the presence of antigen that determines how T cells migrate and interact with the tumor cells.

The fused polypeptide could permeate the tumor cells quickly and mainly locate in cytoplasm, but not in nuclear.

The ultrastructural changes of tumor cells were observed by electron microscopy.

The antibody for tissue factor inhibited intravascular migration of tumor cells.

Immune cells called T lymphocytes recognize invaders in the body, such as viruses, bacteria, tumor cells, or allergens.

Cisplatin and other platinum-based cancer drugs destroy tumor cells by binding to DNA strands, interfering with DNA replication.

As a tumor-suppressor gene, phosphatase and tensin homology deleted on chromosome 10(PTEN) regulates negatively the growth of tumor cells.

Mice were then injected with tumor cells, which led to malignancies in all of the control animals within 15 days.

Autonomous abnormal hyperplasia of malignant tumor cells.

Tyroserleutide decreased the amount of proliferation tumor cells and induced the apoptosis of tumor cells.

Now the toxin in bee venom has been harnessed to kill tumor cells by researchers at Washington University School of Medicine in St.

And, lung tumor cells are diagnosed by their appearance under a microscope.

In contrast, 17 alpha androstenediol inhibits proliferation and mediates apoptosis in tumor cells of murine and human origin.

The inhibitory effect of polysaccharide on tumor cells proliferation was assayed by MTT method.

It blocks tumor cells by stabilizing and polymerizing microtubules.

In immunohistochemical studies, the tumor cells stained intensely and diffusely with smooth muscle actin.

Results: Pathological morphology was seen in the case of angiosarcoma, such as spindle and epithelioid tumor cells.

Add a high-frequency magnetic field, and the particles heat up, raising the temperature of the tumor cells.

Recent progress in molecular techniques has demonstrated the presence of micrometastatic tumor cells in SLNs.

Thyroid tumor stem cells similar to thyroid stem cells in thyroid are origin of thyroid tumor cells.

Primary expression of benign interstitial tumor cells .

Because tumor cells are genetically unstable, they may easily find ways to bypass the antiangiogenesis drugs, Tabar says.

OBJECTIVE: To explore the mechanism of killing tumor cells by observing the C6 rat glioma cell apoptosis after cryotherapy .

T. spiralis infection can reduce tumor growth to various extents in mice bearing tumor cells at different times post infection.

Alginate bead assay was designed to measure in vivo angiogenesis induced by tumor cells.

Hepatoma cells are differentiated tumor cells derived from liver.

CONCLUSION The strain prepared in our lab can kill various tumor cells and possesses a potential clinical significance.

The fibroblasts, in turn, send signals to the tumor cells to stimulate their growth.

Atypical appearances of malignant tumor cells .

Tumor cells are extremely mobile and "adept" at penetrating healthy tissue to form metastases.

Primary expression of benign epithelial tumor cells.

Objective: To observe the effect of Newcastle Disease Virus(NDV) on the immunogenicity of in vitro tumor cells.

The major cause of low survival rate in lung cancer patients is the metastasis of tumor cells.

When the T cells recognized the antigen, they interacted directly with the tumor cells.

Distribution changes of malignant tumor cells.

Quantitative changes of malignant tumor cells.

They've found that turmeric's active ingredient, curcumin, works in the lab to fight skin, breast and other tumor cells.

The effect of PEG-IFN was better than the effect of IFN in inhibiting tumor cells.

The dead tumor cells are gradually replaced by scar tissue that shrinks over time.

It also can inhibit growth of xenograft tumor in athymic mice, accelerate necrosis and apoptosis of tumor cells.

As a result, dormant tumor cells have become a crucial target for preventing and treating cancers.

It may be one reason for immune escape of tumor cells that induces the development and metastasis of tumor.

Staining more than 5% of tumor cells was recorded as positive immunoreactivity.

Could the therapy kill all tumor cells without damaging normal cells?

Tumor cells, like bacteria, can develop resistance to drugs.

With this model we can observed the tumor cells invasion, breaking through the basement membrane and early stage of blood metastasis.

Radiosensitizers are drugs that make tumor cells more sensitive to radiation therapy.

The tumor cells were focally positive for CD68 immunostaining, suggesting possible histiocytic origin.

Tumor cells can travel through the blood vessels.

Tumor cells that spread to other sites somehow escape anoikis.

The same object of all kinds of targeting therapy is to kill tumor cells specifically and to reduce the side effect on normal cells.

After treatment with herbs, CTLs from mice spleen have stronger toxicity for tumor cells in vitro.

Overall the tumor cells are fairly uniform in nuclear size and shape.

AIM: To evaluate the effect of tissue factor on intravascular migration of tumor cells.

Results: The resistance reversal agent of cancer cell can increase the tumor cells sensitivity to medicine in order to reach reverse action.

Allicin has even been shown to kill tumor cells in certain studies.

Ever wondered what it looks like when tumor cells grow inside the body?

RESULTS: High expression of tissue factor was observed in tumor cells (HT1080).

Nuclear changes of malignant tumor cells.

Perforin and granzyme are important effector molecules in cytolytic cells. They can induce apoptosis of tumor cells and infection cells.

The antibody to MMP-9 could decrease the invasion and metastasis ability of tumor cells.

Flavonoids extract purified by ADS-17 macroporous resin has inhibitory effect on tumor cells and can induce apoptosis in vitro.

In this way, the membrane fluidity of living Ehrlich ascites tumor cells was determined.

Size and shape changes of malignant tumor cells.

Resulting in the death of the tumor cells.

Transfected with P53 gene made tumor cell apoptosis and cut down the expression of NKG2D ligands in tumor cells.

The radiosensitivity of tumor cells are different, the difference may come from their own.

Once ice balls are formed, tumor cells will be frozen.

In the fully nourished mice, only 3 percent of tumor cells were dying.

Because of the complexity of the tumor, tumor system not only contains the tumor cells, and also contains immune cells.

In 31 patients, 14 patients underwent surgical operation, among them, 4 were found without obvious tumor cells.

The tumor cells almost infect the EBV 100%. There is some immunogenicity in the viral protein, which is the ideal tumor antigen.

And the first thing that makes me think is that blood vessels are like highways for the tumor cells.

For example, tumor cells can signal nearby blood vessels to grow in their direction, thereby facilitating tumor growth.

Many people assume if you enhance the immune system it will kill off tumor cells. That is not necessarily the ease.

Not only can the cryosurgery kill the tumor cells directly, it can make the human body to activate T cellular immunity as well.

Because some tumor cells such as hydatidiform mole, choriocarcinoma, bronchial cancer and renal cell carcinoma, but also can secrete HCG.

By increasing the level of genetic damage, we can kill those tumor cells.

Objective To study the adhering of red blood cells and lymphocytes to tumor cells from the patients of advanced liver cancer.

To study the inhibition of Brucea Javanica Emulsion (BJE) on HPV positive tumor cells from laryngeal papilloma in vitro.

Fluorescent dye of CFSE used for labeling tumor cells and determining cytotoxicity

Primary Study of the Relationship Between Aneuploidy and Proliferation Phenotypes of Tumor Cells

Expression of telomerase activity in circulating tumor cells of patients with colorectal carcinoma and its clinical significance

Inhibitory effects of the adriamycin magnetic albumin microspheres combined with the constant magnetic fields on the malignant tumor cells

Experimental study of electrochemotherapy on implanted liver tumor cells apoptosis of rats

The Cytotoxic Effects of the Adriamycin Magnetic Albumin Microspheres Combined with External Magnetic Fields on the Malignant Tumor Cells

Construction of a New Kind of Recombinant Adenovirus and Its effect on Tumor Cells

Study on construction of prokaryotic vector for expression of a protein inducing apoptosis of tumor cells

Experimental study of enhanced gene delivery to cultured tumor cells in vitro by ultrasound and contrast agent

Characteristics of metastatic tumor cells in bone marrow of patients with gastric cancer and its clinical significance

Folate Receptor and Its Application in the Selective Receptor-mediated Targeting Therapy of Tumor Cells--Review

Study of the direct inhibition of tumor cells mediated by human dendritic cells in vitro

No touch isolation technique reduces intraoperative shedding of tumor cells into the portal vein during resection of colorectal cancer

Experimental study of tissue factor pathway inhibitor-2 expression inhibiting the invasive potential of human ovarian tumor cells

Correlation of in vitro Chemosensitivity Between Peripheral Blood Lymphocytes and Tumor Cells of Patients with Esophageal Carcinoma

Biological Characteristics of Transferable Bladder Tumor Cells and Preliminary Established Animal Model

Indirect Moxibustion on Hypoxic Tumor Cells and Immunological Function of Tumor Undergoing Radiotherapy

Expression of augmenter of liver regeneration in hepatic tumor cells and its clinical significance

Changes in biological features of remnant tumor cells after treatment with microwave ablation and effects of the treatment on body

The influence of bFGF and its receptor on the angiogenesis and proliferation of tumor cells in human astrocytoma

Inhibition of Malignant Tumor Cells Growing in vitro by Chemical Method Through Increasing Intercellular Communication

Adenovirus mediated double suicide gene under controlling by KDR promoter kills selectively vein endothelial cells and solid tumor cells

Detection of tumor cells in peripheral blood of patients with Ewing's sarcoma and its clinical significance

The Linear Relationship Between Chromosome Induced-Translocation And Radiosensitivity of Human Tumor Cells

Correlation study on the chemosensitivity in vitro by peripheral blood lymphocyte and tumor cells of patients with cardiac carcinoma

Detection of tumor cells in the peripheral blood of the patients suffered from gestational trophoblastic tumor

Effect of low molecular weight nature tumor suppressor of fetal liver on proliferation and differentiation of the tumor cells

Study on detecting the sensitivity of tumor cells to chemotherapeutic agents by immunohistochemical staining with anti-ssDNA mAb

Apoptotic susceptibility of the tumor cells to arsenic trioxide is associated with the inherent level of cellular reactive oxygen species

An experimental study of human neutrophil peptides against tumor cells

Mathematical Analysis of a Model of a Replication-competent Virus in Tumor Cells

Significance of detecting disseminated tumor cells in peripheral blood of patients with colorectal carcinoma

Significance of detecting disseminated tumor cells in peripheral blood of gastric and colorectal cancer patients

Prostate Cancer Bone Metastasis: Interaction Between Tumor Cells and Bone Microenvironment

Expression of endogenous dopamine toxicity induced by human tyrosine hydroxylase in mouse pituitary tumor cells

Effects of different number of tumor cells on xenograft tumor growth and efficacy of anti-tumor agents in mice

Establishment of cellular nitric oxide donor and its apoptosis-induction effect on tumor cells

Transfection of nerve growth factor gene in neuroblastoma cell line induces neuronal differentiation of tumor cells

Effects of medicated rat serum of traditional Chinese herb decoction on proliferation of ovarian cancer fresh solid tumor cells

Synthesis of RGD identical-fork-peptide derivative with inhibitive effect on adhesiveness of advanced metastatic tumor cells

Study on the Mechanism of Differentiation and Apoptosis of Tumor Cells Induced by Effective monomers of Chinese Medicina Herbs

Evaluation of diagnosing disseminated tumor cells by nested RT-PCR in peripheral blood and bone marrow from patients with lung cancer

Extract from cultured cells of Taxus chinensis on proliferation inhibition and apoptosis induction of tumor cells

The phenomena and the significance of erythrocytes lymphocytes and granulocytes immune-adhering tumor cells in self-plasma

Identification of telomerase catalytic subunit hTERT gene promoter binding factors in human tumor cells

In Vitro Research on the Effects Against Drug-Resistant Tumor Cells of Nine Active Components of Traditional Chinese Drugs

Telomerase Activity in Malignant Tumor Cells During Differentiation Induction in Vitro

Experimental study on the chemosensitivity of peripheral blood lymphocytes and tumor cells of lung cancer in vitro

Structures, physics-chemical properties and inhibiting effects of the amine stearo-platinum complexes on tumor cells

Purification of HSP70-PCs from esophageal tumor cells and detection of its anti-tumor activity to the tumor cells

Effects of hepatic stimulating substance on the proliferation of hepatocytes and hepatic tumor cells

Impact of neoadjuvant chemotherapy on proliferative of tumor cells in tongue squamous cell carcinoma