PC12 Cells

METHODS: PC12 cells were treated with different concentrations of glutamate as an in vitro excitotoxic trauma model.

These results demonstrate that the morphologically differentiated neuronal PC12 cells still retain the ability to divide.

Results Results showed that methylmercury inhibited the neurite outgrowth and survival of PC12 cells.

CONCLUSION It indicates that panaxynol has neurotrophic and neuroprotective effects on PC12 cells.

OBJECTIVE To investigate the neurotrophic and neuroprotective effects of panaxynol on PC12 cells.

Conclusion Prion protein 106-126 peptide can induce apoptosis in differentiated PC12 cells and present cellular toxicity definitely.

Objective To investigate the effects of prion protein 106-126 peptide on inducing apoptosis in differentiated PC12 cells.

The viability of PC12 cells was observed by the trypan blue dye exclusion assay.

The retrieved encapsulated PC12 cells were recultured and their activities were tested by MTT and Trypan blue test.

The well growth and the good biological activities of the retrieved PC12 cells were proved using the MTT and Trypan blue test.

Conclusions Acting on PC12 cells for a while, Manganese could inhibited the growth and livingness of PC12 cells in dose and time-dependent;

Conclusions(1) Manganese chloride can inhibited the growth and livingness of PC12 cells in a certainty condition;

the immediate early genes expression in the pc12 cells activated by anatoxin - a

MTT colorimetry tests were performed to exam cell growth and livingness of PC12 cells in various dose of Manganese;

There are some contradict effects of astragalus in the apoptosis by manganese chloride in some extent dose in PC12 cells;