MMP 9

Objective: To investigate the significance of matrix metalloproteinase-9 expression in human oral carcinogenesis and precancerous lesion.

It is associated with atherosclerosis, and plays an important role in weakened fibre cap, disruption of plaque, and acute coronary syndrome.

MMP-9 and metastin could be a marker to evaluate metastasis and invasion in renal clear cell carcinoma .

This article reviewed the role of MMP-9 expression in osteoclast and its regulation mechanism in recent years.

They found astrocytes close to amyloid plaques increased their MMP-9 production.

The invention also discloses a method for screening substances having the function of inhibiting the MMP-9 enzymatic activity.

MMP-9 can be applied to differentiate benign tumors from malignant ones.

Gelatin zymography was used to measure blood levels of circulating matrix metalloproteinase-9 (MMP-9).

It's possible to provide new proofs for research on pathogenesis and therapy of phosgene-induced lung injury by studying the role of MMP-9.

Aim: To explore the effects of calcitonin-gene-related peptide(CGRP) on LPS-induced MMP-9 secretion by alveolar macrophages(AM)in vitro.

Conclusion OPN and MMP-9 play a synergistic role in the genesis, development, invasion and metastasis of cervical carcinoma.

Studies recently show that MMP - 9 of the family connected closely with the brain edema following ICH by over - degrading the ECM.

Results MMP-2 and MMP-9 were expressed in the proliferative phase of normal endometrium, but almost not in the secretory phase.

Matrix metalloproteases MMP-2 and MMP-9: Are they early biomarkers of bone remodelling and healing after arthroscopic acromioplasty?

Objective: To investigate the expression of difference MMP-2 and MMP-9 of matrix metalloproteinases in nasal inverted papilloma(NIP).

We previously found that a membrane-anchored glycoprotein, RECK, negatively regulates MMP-9 and inhibits tumor invasion and metastasis.

Conclusions: The decline of MMP-9 expression after HBOT may contribute to protection of brain tissue in the perilesional area.

Results The serum levels of MMP-9 in IPF were significantly higher than that of healthy control, with significant difference (P01).

The antibody to MMP-9 could decrease the invasion and metastasis ability of tumor cells.

MMP - 9 was expressed in the cytoplasm of sinusoidal cells and hepatic cells around vein.

MMP-2 and MMP-9 may be used as valuable biological markers for predicting progression of colorectal neoplasm into carcinoma.

Thus MMP-9 might not be a major gene for asthma.

Conclusion: Hypoxia and microenvironment pressure of tumor can increase MMP-2 and MMP-9 expression and influence the LPPCN formation.

Maximal MMP-9 was seen at 0-12 h and was elevated when compared with control (P = 0. 002) followed by fall to a plateau.

Objective To explore the influence of MMP 2 and MMP 9 on invasive microecosystem of human brain glioma.

It was found that the expression level of both MMP-2and MMP-9of patients with OA were significantly higher than that of controls(P0. 05).

Conclusion The left ventricular dyssynchrony is closely related to the level of MMP-9 of rats with heart failure.

Conclusion MMP-2 and MMP-9 could promote the development and progression of endometrial adenocarcinoma.

To study the expression of matrix metalloproteinase (MMP)-2 and -9 and its significance in benign breast disease and breast carcinoma.

Objective: To study the change in matrix metalloproteinase-9 (MMP-9) expression in primary and recurrent human gliomas.

Expression of MMP-9 and its correlation with cancer cell proliferation and metastasis in oral squamous cell carcinoma

Relationship between preoperative staging of endoscopic ultrasonography and genic expression of MMP-9 in gastric carcinoma

Ischemic Preconditioning Influences Blood-Brain Barrier Permeability and MMP-9 Expression of Ischemic Brain

Influence of moderate copper deficiency on expression and activity of MMP-9 and restenosis in balloon-injured rat carotid arteries

Changes and Significance of MMP-9 After Conventional Stenting and Direct Stenting for Patients with Coronary Heart Disease

Expression of MMP-9 in transitional cell carcinoma of bladder and its significance

Effects of mild hypothermia on MMP-9 expression and brain edema following focal cerebral ischemia-reperfusion in rats

Relationship between expression of MMP-9, FAK and lymphnode metastasis of tongue squamous cell carcinoma

Detection of serum total MMP-9 and its clinical significance for lung neoplasms

The Significance of Expression of Extracellular Matrix MMP-9 in Mucinous Tumors of the Ovary

Relationship between MMP-9 Expression and H. Pylori Infection in different Gastric Mucosa Lesions

Significance of Detecting MMP-9 in the Cerebrospinal Fluid of Patients with Tuberculous Meningitis

Expression of MMP-9 correlates with lymph node metastasis and prognosis in gallbladder carcinoma

Expression and clinical significance of MMP-9 in serum of ischemic cerebral vascular disease patient

Significance and effect of mild hypothermia on the LN and the MMP-9 expressions after focal cerebral ischemia and reperfusion in rats

Relationship between MR perfusion weighted imaging and expression of MMP-9 in human astrocytoma

Expression of MMP-9 in skin squamous cell carcinoma and its significance in microangiogenesis

Relationship between MMP-9 expression and the sub-types of peripheral venous malformations

The expression and clinical significance of VEGF and MMP-9 in primary hepatocellular carcinoma

Inhibitory effects of antisense MMP-9 oligodeoxynucleotides on invasiveness and adherence of ovarian cancer cells

MMP-9 changes after cerebral stroke and intervention study with Batroxobin injection

Effects of Lipopolysaccharides on Expressions of MMP-9 and the Possible Molecular Mechanism

Studies on the Expression of MMP-9 and Infiltration of Macrophage in Oral Squamous Cell Carcinoma

Expression of MMP-9 in the Periodontal Tissues during Experimental Tooth Movement in Rabbit

Serum MMP-2 and MMP-9 levels correlated with the disease activity and progression of joint damage in early rheumatoid arthritis

The expression of VEGF and MMP-9 in gastric carcinoma and their roles in invasion and metastasis

Clinical Significance of Detection of Serum MMP-9 in Pulmonary Tuberculosis

The Relationship between Serum MMP-9 Concentration and Risk Stratification of Unstable Angina Pectoris

Expression of MMP-9 and their Clinical Significance in Cervical Carcinoma

The value of serum MMP-9 concentration in the diagnosis of recurrence of endometriosis after operation

Effects of HCV persistent infection on synthesis and secretion of MMP-2 and MMP-9 of human placental syncytiotrophoblast in vitro

Effect of MMP-9 and MMP inhibitor on severe acute pancreatitis associated with lung injury in rats

Expression of MMP-9 in bronchial biopsy mucosal tissue in asthmatic subjects

Clinical Significance of Expression of MMP-9 in Human Thyroid Carcinoma

Effects of Astragalus and saponins of Panax notoginseng on MMP-9 in patients with type 2 diabetic macroangiopathy

MMP-9 expression in brain after superior sagittal sinus obstruction in rats

The Significance of MMP-9 Examination in Serum from Embryo of Gastric Cancer Model

Clinical significance of MMP-9 expression in human gastric cancer

Effect of Cerium on Expression and Activity of MMP-9 from Human Carcinoma of Bladder Cell Line

Value of MMP-9 in early severity assessment of acute pancreatitis

Effects of Naoshuning on permeability of blood-brain barrier and MMP-9 expression in TBI rats

Relationship between serum MMP-9 and TIMP-1 and carotid intimal-medial thickness in newly detected type 2 diabetic Patients

Relationship between serum MMP-9 and TIMP-1 in the patients with diabetic retinopathy

Effects of aspirin on promoter activities of human MMP-9 gene

The role of changes of MMP-2, 9 activity in the development of liver fibrosis in rats