hair cells

In one study, a team member found a type of protein increased in a chick (which can regenerate hair cells) after its cells were damaged.

The hope was that the Math1 gene would be activated in the infected cells, which would then grow cilia, thus becoming hair cells.

Then, researchers around the country began observing that hair cells grew back in birds whose hearing was damaged either by noise or drugs.

One finding identified a developmental protein that appears to be turned on in animals able to regenerate hair cells.

Our work shows that it is possible to produce functional auditory hair cells in the mammalian cochlea.

The presence of outer hair cells makes mammalian hearing more than 100 times better than it would be if the cells were absent.

As older hair cells move toward the surface of you your skin, they change.

These mechanoreceptor organs, like the hair cells in the human ear, mechanically transmit the stimulus of touch or sound waves.

in experiments, song birds that had grown new hair cells were able to resume singing their original songs with perfect pitch again.

One of the roadblocks to understanding the molecular basis of hearing is the paucity of hair cells available for study, Heller said.

Until the mid-1980s, researchers thought warm-blooded vertebrates, including humans, weren't able to regenerate hair cells.

They are thought to be produced by the motion of hair cells within the outer part of the cochlea.

Thesemechanoreceptor organs, like the hair cells in the human ear, mechanicallytransmit the stimulus of touch or sound waves.

In many cases of non-congenital hearing loss, the cause is degeneration of specialized sensory cells in the inner ear, called hair cells.

But unlike humans, zebra fish are able to regenerate their damaged hair cells.

More importantly, further study showed that the cells also responded to mechanical stimulation by producing currents just like hair cells.

Surrounding cells known as support cells can both turn into hair cells or generate new hair cells.

Preliminary study of the effect of cisplatin on Kca channels of isolated guinea pig cochlear outer hair cells .

Objective To observe the morphological features of the normal and anomalous stereocilia of cochlea hair cells.

Often, the reason is damage to specialised sensory cells known as hair cells.

The lab's research into the regeneration of hair cells for transplantation into the inner ear to cure deafness will also continue.

In this paper, we identified two microRNAs that, when removed, reduced the number of hair cells developed.

This was a new field at the time, and no one believed that hair cells could regrow after damage.

They were treated with antibiotics, to kill their hair cells. This made them completely deaf.

We have used this model to screen for and identify multiple drugs that protect hair cells from aminoglycoside-induced death.

Researchers hope their work can unlock secrets to protect human hair cells from becoming damaged and to stimulate the cells to regenerate.

The results show that inner hair cells is sensitive to low frequency, which produces to the environment adaption.

In this experiment, zebra fish are exposed to a dye that highlights living hair cells.

Damaged hair cells in the inner ear are associated with permanent hearing loss, as hair cells cannot regenerate or be replaced.

Outer hair cells and the stereocilia are arranged not regular, There were less stereocilia missing at top turn and basal turn of cochlea.

Since then, his research has focused on using these stem cells to regenerate the critically needed hair cells in the inner ear.

The number of new hair cells expanded, along with restoration of hearing.

This study thus examined the potential of hydrogen to protect auditory hair cells from ROS-induced damage.

These findings show the potential of hydrogen to protect auditory hair cells from ROS -induced damage.

Those chemicals found to confer protection on fish hair cells are currently also being tested on mice and rats.

Different chemicals are administered to each fish group that might confer protection to the hair cells.

Stress syndrome can lead to disease bald human immune system error against the scalp hair cells, causing large fall off.

Theability of the hair cells to regenerate also deteriorates and hair loss is common, often seen as patches of hair loss.

John Brigande and colleagues at Oregon Health & Science University used gene therapy to restore the cochlear hair cells in mice.

It has been discovered that a shark senses pressure using hair cells in its balance system.

Chickens, like all birds, have the ability to spontaneously regenerate these hair cells, which explains why there are no deaf birds.

According to the NIDCD, excessive noise, certain medications, aging and disease can damage or destroy hair cells.

But there is no indication that mammals can regenerate hair cells.

Conclusions The irregular arrangement and natural loss of stereociliary bundles of the outer hair cells are not pathological changes.

The inner ear contains tiny hair cells that deform when sound waves hit them.

Finally, another chemical known to kill the fish hair cells is added.

In addition, we will learn how the connection between hair cells and otic neurons is established.

RESULT: The tall hair cells reacted more strongly than the short hair cells.

Reactive oxygen species (ROS) play a role in the degeneration of auditory hair cells because of aging, noise trauma, or ototoxic drugs.

There are two main approaches to efforts aimed at inducing hair cells to regenerate.

Humans are born with 30, 000 cochlear and vestibular hair cells per ear.

Bernstein says Latisse in fact does work because it is changing the molecular structure of the hair cells.

That is because the treatment only caused the regrowth of a group of cells called the inner hair cells.

AIM: To study the changes of K channels of outer hair cells in guinea pig cochlea with streptomycin ototoxicity.

Response Characteristics of the Guinea-pig Cochlea Outer Hair Cells and Its Alteration Induced by Intense Tones: Intracellular studies

Time sequential analysis of the death of rat's cochlear outer hair cells at the early stage after exposure to impulse noise

Experimental study of sodium nitroprusside on whole cell calcium currents of outer hair cells in the cochlear of guinea pigs

Quantitative study of cochlear hair cells injuries in guinea pigs exposed to blast underpressure

Cochlear slices technique in vitro for observing the morphologic structure and electrophysiological characteristics of outer hair cells

Cholinergic Regulation of Intracellular Free Calcium Concentrations in the Isolated Outer Hair Cells of the Guinea Pig Cochlea

Isolation of and intracellular calcium mobilization in vestibular hair cells of the patients with acoustic neuroma

Differential Vulnerability of Inner and Outer Hair Cells of the Guinea Pig Cochlear to the Ectogenesis Glutamate

Increase of intracellular calcium concentration in vestibular hair cells induced by cholinergic agonists and the effects of gentamicin on it

Effect of Electroacupuncture on Succinate Dehydrogenase of Gentamycin Induced Ototoxic Cochlear Hair Cells in Guinea Pigs

Effects of ACh on Voltage- dependent Outwardly Rectifying Potassium Currents in Isolated Outer Hair Cells in Cochlea of Guinea Pig

Effects of Streptomycin on Calcium-Sensitive Outward Potassium Currents in Isolated Outer Hair Cells of Guinea Pig Cochlea

Intracellular calcium mobilization and effects of ATP on ampullate crista hair cells of the guinea pig

Quantitative observation of carboplatin induced early damage in chinchilla hair cells and nerve fibers

The dynamic changes of glutamate-like immunoreactivity in cochleae inner hair cells of guinea pigs after noise exposure

Neurotrophins decrease degeneration of out hair cells of the guinea pig after noise trauma

Extracellular cisplatin inhibit KCa current from isolated guinea pig cochlear outer hair cells

Regeneration of cochlear hair cells of guinea pigs following gentamicin ototoxicity

Effects of salvia miltiorrhizae injection on succinate dehydrogenase in the cochlear hair cells of the guinea pigs

Carboplatin-induced injury patterns of inner hair cells missing in chinchilla cochlea

The influences of infrasound on auditory threshold and morphology of cochlea hair cells in guinea pigs

A quantitative study on cochlear hair cells and spiral ganglion cells after blast exposure in guinea pigs

Death mode of outer hair cells in chinchilla cochlea after exposure to difference levels of intense noise

Outwardly rectifying potassium currents in isolated outer hair cells in cochlea of guinea pig

Apoptosis of guinea pig cochlear hair cells following netilmicin treatment

Identification of damaged hair cells in the cochlea by double staining with TUNEL and propidium iodide

Activation of JNK Expression in Cochlear Hair Cells of Guinea Pigs With Amikacin Ototoxicity

Effects of noise exposure on glutamate-like immunoreactivity of inner hair cells in guinea pigs

Effects of exposure to moderate blast underpressure on calcium ion of cochlea hair cells in guinea pig

Apoptosis of Guinea Pig Cochlear Corti's Hair Cells Following Gentamicin Treatment

Distribution of L-type calcium channels on outer hair cells among various turns of guinea pig cochlea

Application of rat tail collagen in patch clamp experiment with vestibular hair cells

The biophysical properties of transduction in cochlear hair cells

Experimental study on influence of vancomycin on the mouse cochlear hair cells in vitro

Isolation of outer hair cells from varying turns of the guinea-pig cochlea

Observation of Calcium Waves in Isolated Outer Hair Cells of Guinea Pig Cochlea

Effect of potassium ion concentration on apoptosis in cochlear hair cells in vitro

Comparison of three methods for detecting the death modes of hair cells in the cochlea

Potassium channels in outer hair cells of the guinea pig's cochlea

Amikacin- induced apoptosis in cochlear hair cells in guinea pigs

Quantified Analytic System for Cochlear Hair Cells

Isolation of Cochlear Outer Hair Cells from Guinea Pigs by Trypsin

The method of detecting the apoptotic hair cells at their early stage in the cochlea

Influence of exogenous glutamic acid on cochlea inner ear hair cells and hearing threshold

Regeneration of Hair cells in newborn rat cochlea

Effect of amikacin on the cochlear hair cells and hearing threshold ofguinea pigs

Effect of hypoxia on cultural hair cells of rat cochlea in vitro

For DFgroup and Fgroup, outer hair cells arranged irregularly and few cells loss;