histone

and the DNA is wrapped around the histones like a few wraps of thread around a spool.

Sometimes a physical gap where the DNA floats free of any histones can halt the spread, Bi says.

Chromatin contains half as much DNA as it does protein, most of which is in the form of histones .

Histones are protein- found in eukaryotic cell nuclei, tightly bound to DNA, which has many phosphate groups.

Histones also play a role in turning genes on so that their coded instructions can be copied and sent to other parts of the cell.

Epigenetic marks, such as the modifications of the histones, are also important for the specialisation of the body's cells.

An octa-mer of histones package DNA into a structure called a nucleosome.

MOTIVATION: Post-translational modifications to histones have several well known associations with regulation of gene expression.

A chromosome is made up of genetic material (one long piece of DNA) wrapped around structural support proteins (histones).

This epigenetic information can be introduced by cytosine methylation and by marking nucleosomal histones.

DNA wraps around histones in left-handed way and forms nucleosome structure. Many nucleosomes are linked together like "prayer beads" .

Covalent modification of histones on chromatin is a dynamic mechanism by which various nuclear processes are regulated.

Each long strand of DNA combines with histones and nonhistone proteins to make up the substance chromatin.

Histones are a group of proteins that are associated with chromosomes.

The proteins that combine with DNA are generally of characteristic types called histones and protamines.

Histones package DNA, and post- translational modifications of histones can regulate access to DNA.

Histones make up the spool of proteins around which DNA winds so that it is packaged compactly in the nucleus.

At the same time, we simulate the interaction between DNA and a few histones.

Luger and her colleagues next packaged the modified histones they received from Shokat's group into recombinant nucleosomes and chromatin.

HISTONE: Histones are crucial in the process of condensing and packing DNA within a cell's nucleus.

Histones are the basic packaging units for DNA and they undergo post-translational modifications.

Histones are proteins that regulate DNA packing, and histone deacetylases are enzymes that control the way those proteins work.

Histones wrap DNA to form nucleosome particles that compact eukaryotic genomes.

Matthew Simon, a postdoctoral fellow in Shokat's laboratory, produced pure samples of H3 and H4 histones with the desired methylation marks.

Histones are nature's answer to the question: How does a cell fit 1. 8 meters of DNA into its nucleus?

In age-related memory loss, the H4 histones don't have enough acetyl groups attached to them.

For example, they found that proteins called histones, which help control a gene's activity, were being altered.

when DNA is wrapped tightly around the histones, genes are hidden,

The histones are kind of like the spool,