Once gangrene has developed, the tissue is dead.一旦出现坏疽, 机体组织便死亡了。

The gangrene of the aristocracy and bourgeoisie should be amputated from the State.国家应该铲除贵族和资产阶级的道德败坏作风。

His leg gangrened.他的一条腿生坏疽了。

Discontent has gangrened into desperation.心怀不满已经发展成了铤而走险。