to do something that has a big effect and after which it is very difficult or impossible to go back to how things were before把魔鬼从瓶子里放出来（比喻引发难以遏制的灾难性后果）
When guns were invented, the genie was let out of the bottle.当枪给发明出来的时候，便是不可控恶果的开始。
This idiom can be expressed in various different ways. Other versions include the genie is out of the bottle and opposite form put the genie back in the bottle. Many people realized the genie was out of the bottle and that free music and movie downloads were here to stay. • The world has failed to put the nuclear genie back in the bottle.