sadShe's been sad ever since her cat died.
unhappyShe'd had a very unhappy childhood.
miserableI just woke up feeling miserable.
upsetThey'd had an argument and he was still upset about it.
broken-heartedShe was broken-hearted when her partner left.
heartbrokenHis girlfriend dumped him, and he's been heartbroken ever since.
heartsickliteraryShe was heartsick when the regiment went away.
devastatedHe was devastated when he lost his house.
distraughtShe was distraught over the article and feared losing her job.
depressedIt makes her depressed to think about the injury.
lowHe was very low for months after he lost his job.