The immunogenicity of 12F6 in humans has been reduced though humanization. But the first-dosereaction associated with T cell activation by anti-CD3 Abs still exists.
人源化抗体解决了抗体鼠源性的问题，但CD3单抗激活T细胞引起首剂效应的问题仍然存在。
2
The results show that the degradation efficiency of DBS increases with the accretion of radiation dose of gamma rays and the degradation reaction of DBS seems following first-order kinetic.