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医药科学 脓毒症 In recent years, activated protein C attracted more attention in the treatment of infectious diseases, especially in the treatment and prevention of pyaemia, endotoxin blood poisoning and disseminated intravascular coagulation in endotoxemia. 近年来,活化蛋白C在感染性疾病,特别是在严重脓毒症、内毒素血症和弥散性血管内凝血等严重感染性疾病中的治疗备受关注。 药物 Endotoxemia is a common and complex problem for medicine,and drug therapeutic efficacy is not very well. 内毒素血症是医学临床面临的一个常见而复杂的难题,药物治疗效果不佳。 脓毒血症 Conclusions:Direct hemoperfusion with PVDF-Ser column effectively adsorbed endotoxin in vivo,had an inhibitory effect on plasma cytokines and reduced the inflammatory responses and mortality in endotoxemia. 结论:应用PVDF-丝氨酸吸附膜进行血液灌流,可以有效清除内毒素,降低TNF-α和IL-6,减轻炎症反应,降低脓毒血症的死亡率。 内毒素血症
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