OBJECTIVE to explore the effect and significance of platelet activating factor (PAF) on prostaglandinE2 (PGE2) synthesis in rat glomerular mesangial cell (GMC) in culture.
Objective To investigate the effects of mechanical damage on prostaglandinE2 (PGE2) secretion in human skin keratinocytes, and explore its possible mechanism.
目的探讨机械损伤对人皮肤角质形成细胞前列腺素e2 (PGE2)分泌的影响及其可能的机制。
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Conclusion Celecoxib may reduce the accumulation of prostaglandinE2 by inhibiting cyclooxygenase-2 activity, and thus inhibiting the expression of VEGF.