In most species, the kidney is both the sensor organ and the major site of erythropoietin production, so chronic renalfailure is associated with anemia.
大多数物种中，肾脏既是促红细胞生成素的感受器官又是产生的主要场所，所以慢性肾功能衰竭会导致贫血。
3
Further, the sudden release of toxins from necrotic muscle into the circulatory system leads to myoglobinuria, which causes renalfailure if untreated.