Objective To Study sensitive mark ofbiochemistryofbone metabolize of The Endemic Fluorosis by epidemiology examine and lab check up in high fluorine area of drinking water.
目的对饮水型高氟病区进行流行病学调查及实验室检测，研究地方性氟中毒患者骨代谢的生化敏感标志物。
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Methods: Using X-ray; bone mineral density index and bonebiochemistry measure 369 cases of old fracture who have been fracture in three years through means of Evidence-based medicine.
Measurement of biochemical markers ofbone metabolism: Serum Ca, P, ALP and TRAP was measured by automatic biochemistry analyzer, BGPmeasured by radioimmunoassay;