Kinetics and mechanism of nanoparticle-mediated cellular drug delivery and therapeutic efficacy of nanoparticle-encapsulated doxorubicin were evaluated in two model breast cancer cell lines.
用两种乳腺癌细胞株模型评价纳米粒介导的细胞药物释放动力学和机理及纳米粒包囊阿霉素的治疗效果。
2
OBJECTIVE: To investigate the absorption kinetics of danshensu at different intestine segments in rats and the influence of the drug concentration on the absorption kinetics.
目的：考察丹参素在大鼠各肠段的吸收动力学特征及不同药物浓度对其的影响。
3
Optimal estimates of the model parameters were obtained by minimizing the difference between model simulation and experimentally measured drug release kinetics.