Objective to study antitumor effect of calciumfolinate (CF) and 5 fluorocytosine (5 FU) on rectal carcinoma cells transfected with cytosine deaminase (CD) gene.
CONCLUSIONS: MTX serum concentration monitoring is helpful for mastering the rational rescue dosage of MTX and calciumfolinate so as to ensure the efficacy and safety of the chemotherapy.
Objective: to evaluate the efficacy and toxicity of oxaliplatin (L-OHP) combined with calciumfolinate (CF) and fluorouracil (5-fu) in treatment of old patients with advanced colon cancer.