Cells from at patients display defectiveDNA damage-induced checkpoint activation, sensitivity to radiation, and a higher frequency of chromosome breakage (3, 4).
However, some investigators demonstrated that glioma stem cells are radiosensitive with a defectiveDNA damage response compared with established glioma cell lines.
但是最近有研究表明，胶质瘤干细胞并不一定比传统胶质瘤细胞系抗拒。
3
Parliament has ruled that inherited DNA in the mitochondria can be replaced if they are defective and the cause of devastating diseases that are passed down from mothers to their children.