DNA double-strandbreak is probably the most lethal attack, with as little as one unrepaired DSB being capable of triggering programmed cell death.
DNA双链损伤是已知的最严重的细胞损伤,只要有一处未被修复的DSB就能引发程序性细胞凋亡。
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Objective To observe the consistency of DNA double-strandbreak between in vivo and in vitro irradiation, as a prophase study in radiation biodosimetry using single cell gel electrophoresis(SCGE).