释义 |
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化学 脱保护 The reason of the inapparent changes of the rate of transmittance of P(NIPAAm-co-Benzyl A) solution was the insufficiency of deprotection. 发现P(NIPAAm-co-Benzyl A)溶液透光率变化不明显是脱保护不充分的原因。 去保护 Zinc-induced reductive elimination provides 5'-benzoyl ester of Stavudine. Deprotection of Stavudine ester affbrds final product in total yied 42.5%. 溴化甲磺酸酯在锌/乙酸还原消除下得到5’-苯甲酰化的司它夫定,最后去保护得到最终产品司它夫定,总收率42.5%。
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