In one particularly disastrous incident in 1928, 12 children in Australia died from staph infections after getting the diptheria vaccine from the same multi-dose bottle.
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Back in 1921, diptheria caused 206, 000 cases in the U.S. alone.
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One time I was soaking the whole way through and my maw was completely angry, how I was going to die of pneumonia or else diptheria if ye swallowed the water.