Tyr576 and Tyr577 lie in the activation loop of the kinase domain, and mutation of these residues reduces FAK catalytic activity (6).
酪氨酸576和酪氨酸577处于激酶结构域的激活环,这些残基的突变减弱FAK的催化活性(6)。
2
Protein domain analysis showed that ubiquitin-conjugating enzyme genes mainly consist of a big ubiquitin-conjugating enzyme catalyticdomain.
蛋白结构域分析表明,水稻泛素结合酶基因主要由一个泛素结合酶催化结构域组成。
3
This paper reviewed and discussed the mechanism of cellulase hydrolysis, and structures and functions of cellulase catalyticdomain and cellulose binding domain.