Cooling parameters, including cryogenic gas, liquid, temperature of droplet and diameter of droplet, are studied to offer theoretic basis for the next study.

Some of the potential reagents are very fragile and will need to be used at cryogenic temperatures, but the elimination of an atom of an almost inert gas can simplify the chemistry.

To prevent cryogenic liquids or cold gas from being trapped in piping between valves, equip the piping with pressure-relief devices.