After the first flood, Mark, who says he had always been "healthy as a horse," was hospitalized with a severe respiratory virus initially diagnosed as legionnaires' disease.

And the sudden spate of new results mark an acceleration, and perhaps a turning point, in the ability to find disease genes, the long-promised payoff from the human genome project that began in 1989.

Can we work together to cure, prevent or manage all disease within our children's lifetime? Mark and I believe that this is possible.