I met 30 to 40 people suffering from motor neuron disease [which afflicts Hawking] and their families. One person described it as being in a prison cell where your walls just get smaller every day.
Yang JCH, et al. Osimertinib activity in patients (pts) with leptomeningeal (LM) disease from non-small cell lung cancer (NSCLC): updated results from BLOOM, a Phase I study.