In addition to T-lymphocyte participation, mast cells in the choroid play an accessory role with data that degranulation of choroidal mast cells occurred prior to the onset of the disease.

Choroidal neovascularization is the congenerous pathologic pattern of many fundus oculi disease. It is a sign of poor sight or blind of these disease.

The disease which can cause degeneration and broken of bruch's membrane can have choroidal neovascular.