Objective To explore the application of nonlinear mixed models in ordered categorical data of cross-over trial analysis and hence provide methodology reference.
Objective:To explore the application of generalized estimating equation in ordered categorical data of cross-over trial analysis and provide methodology reference.
目的：探讨广义估计方程在交叉试验等级资料中的应用，为临床试验交叉设计资料的正确分析提供方法学参考。
3
Without categorical boundaries, providers would likely submit cross-category bids on many of the projects, making it difficult for buyers to find the right provider.