In the 1960s, M. leprae started to develop resistance to dapsone, the world’s only known anti-leprosy drug at that time.
在1960年代，麻风杆菌开始对世界上当时唯一已知的抗麻风药物氨苯砜形成抗药性。
2
For thosewith negative smears, dapsone and rifampin for one year is the standard of carein the United States.
如果是阴性，服用氨苯砜与利福平1年是标准疗法。
3
Although leprosy was treated differently in the past, the first breakthrough occurred in the 1940s with the development of the drug dapsone, which arrested the disease.