Aim: To investigate the clinical manifestations, pathological changes and diagnosis of congenital fiber type disproportion (CFTD).

Conclusion There is no significant correlativity between congenital heart disease and ABO blood type, so blood type is not an impressionable factor that leads to congenital heart disease.

In current, different kinds of methods were widely used in the animal model, such as the wild type, congenital defect and gene modification.