Combined Molecular and Clinical Prognostic Index for Relapse and Survival in Cytogenetically Normal Acute Myeloid Leukemia.
【译】结合在细胞遗传学正常的急性髓细胞性白血病的分子和复发和生存的预后指标。
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Conclusions Genotypes defined by the mutational status of NPM1, FLT3, CEBPA, and MLL are associated with the outcome of treatment for patients with cytogenetically normal AML.
More importantly, when LSC - and HSC-related gene signatures were examined in a cohort of 160 cytogenetically normal AML patients, both signatures correlated negatively with overall survival.