Constitutive activation of the pathway involving these two genes appears to be a major contributor to the development of uveal melanoma. (Funded by the National Institutes of Health and others. ).
包含这两个基因的信号通路的组成性激活，可能是导致葡萄膜黑色素瘤的主要因素。
2
This signal pathway not only participates in regulating the development of the CNS, but also correlates with the neuron regeneration, development of glioma, and mental deficiency.
此信号通路不仅参与调节中枢神经系统的发育，而且与神经元再生、胶质瘤发生和精神发育迟缓等有关。
3
The development of EGFR and VEGFR pathway antagonists has been blessed by a clear appreciation of the biology targeted by these therapeutic agents.