The objective is to observe the expression of MMP-1and TIMP-1 in nucleus pulposus cells ofintervertebraldiscdegeneration.
目的是测定 MMP-1 及 TIMP-1 在人退变椎间盘髓核中的表达。
2
Spontaneous model with intervertebraldiscdegeneration was the balance of unstability in modal function, while the effect of genetic factor could change this balance and accelerate the degeneration.
Objective. Simulate the reduced glycosaminoglycan content and altered mechanics observed in intervertebraldiscdegeneration using a controlled injection of chondroitinase ABC (ChABC).